196872 BAY 11-7085 - CAS 196309-76-9 - Calbiochem

196872
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Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₁₃H₁₅NO₂S196309-76-9

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196872-10MG
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      Plastic ampoule 10 mg
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      Description
      Overview

      This product has been discontinued.





      We are offering BAY 11-7085 (Cat. No. B5681) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.






      Has biological properties very similar to those of BAY 11-7082 (Cat. No. 196870). In addition, BAY 11-7085 shows potent anti-inflammatory properties in vivo.

      Catalogue Number196872
      Brand Family Calbiochem®
      Synonyms(E)3-[(4-t-Butylphenyl)sulfonyl]-2-propenenitrile
      References
      ReferencesNi, H., et al. 2001. Br. J. Haematol. 115, 279.
      Pierce, J.W., et al. 1997. J. Biol. Chem. 272, 21096.
      Product Information
      CAS number196309-76-9
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₃H₁₅NO₂S
      Chemical formulaC₁₃H₁₅NO₂S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetTNF-α-inducible phosphorylation of IκBα
      Primary Target IC<sub>50</sub>10 µM against TNF-α-inducible phosphorylation of IκBα
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      BAY 11-7085 - CAS 196309-76-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      BAY 11-7085 - CAS 196309-76-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      196872

      References

      Reference overview
      Ni, H., et al. 2001. Br. J. Haematol. 115, 279.
      Pierce, J.W., et al. 1997. J. Biol. Chem. 272, 21096.

      Citations

      Title
    • Zachary T. Resch, et al. (2005) Stress-activated signaling pathways mediate the stimulation of pregnancy-associated plasma protein-A expression in cultured human fibroblasts. Endocrinology 147, 885-890.
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-April-2008 RFH
      Synonyms(E)3-[(4-t-Butylphenyl)sulfonyl]-2-propenenitrile
      DescriptionExhibits biological properties similar to that of BAY 11-7082 (Cat. No. 196870). BAY 11-7085 has also been shown to have potent anti-inflammatory properties in vivo.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number196309-76-9
      Chemical formulaC₁₃H₁₅NO₂S
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesNi, H., et al. 2001. Br. J. Haematol. 115, 279.
      Pierce, J.W., et al. 1997. J. Biol. Chem. 272, 21096.
      Citation
    • Zachary T. Resch, et al. (2005) Stress-activated signaling pathways mediate the stimulation of pregnancy-associated plasma protein-A expression in cultured human fibroblasts. Endocrinology 147, 885-890.