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500299 Nicotinamide

EMPROVE® ESSENTIAL Ph Eur,BP,USP,JP,FCC

Nicotinamide MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Nicotinamide, Niacinamide, 3-Pyridinecarboxamide

CAS #: 98-92-0 EC Number: 202-713-4 Molar Mass: 122.13 g/mol Hill Formula: C₆H₆N₂O Grade: Ph Eur,BP,USP,JP,FCC
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
98-92-0202-713-4C₆H₆N₂O122.13 g/molPh Eur,BP,USP,JP,FCC

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      5002999020
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          Description
          Catalogue Number500299
          SynonymsNicotinamide, Niacinamide, 3-Pyridinecarboxamide
          References
          Product Information
          CAS number98-92-0
          EC number202-713-4
          GradePh Eur,BP,USP,JP,FCC
          Hill FormulaC₆H₆N₂O
          Molar Mass122.13 g/mol
          HS Code2936 29 52
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Boiling point150 - 160 °C (0.0007 hPa)
          Density1.40 g/cm3 (25 °C)
          Flash point150 °C
          Ignition temperature480 °C
          Melting Point130 °C (sublimed)
          pH value6.0 - 7.5 (50 g/l, H₂O, 20 °C)
          Bulk density360 kg/m3
          Solubility691 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat 3530 - 3540 mg/kg
          LD 50 dermalLD50 Rabbit > 2000 mg/kg
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Statement(s)H319: Causes serious eye irritation.
          Precautionary Statement(s)P264: Wash skin thoroughly after handling.
          P280: Wear eye protection/ face protection.
          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
          P337 + P313: If eye irritation persists: Get medical advice/ attention.
          Signal WordWarning
          RTECSQS3675000
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Categories of dangerirritant
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +15°C to +25°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Assay (perchloric acid titration, calculated on dried substance)99.0 - 101.0 %
          Assay (HPLC, calc. on dried substance)98.5 - 101.0 %
          Identity (IR-spectrum) (Ph Eur)passes test
          Identity (IR-spectrum) (USP)passes test
          Identity (coloring 1)passes test
          Identity (coloring 2)passes test
          Identity (UV/VIS-Spectrum)passes test
          AppearanceWhite to almost white, crystalline powder
          Appearance of solution (50 g/l; water)Clear, colourless, not more intense in color than reference solution BY₇
          pH (50 g/l; water)6.0 - 7.5
          Melting range (lower value)≥ 128 °C
          Melting range (upper value)≤ 131 °C
          Absorption ratio (A 245 nm/A 262 nm)0.63 - 0.67
          Chloride (Cl)≤ 210 ppm
          Sulfate (SO₄)≤ 190 ppm
          Pb (Lead)≤ 2 ppm
          Residual solvents (ICH Q3C)excluded by production process
          Readily carbonisable substancepasses test
          Related substances (HPLC) (Major unspecified impurity)≤ 0.10 %
          Related substances (HPLC) (Sum of all impurities)≤ 0.2 %
          Sulfated ash (600 °C)
          ≤ 0.1 %
          Loss on drying (Vacuum; 18 h)
          ≤ 0.5 %
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to Ph Eur, BP, USP, FCC, JP.
          Sulfated ash (600 °C)
          ≤ 0.1 %
          Loss on drying (Vacuum; 18 h)
          ≤ 0.5 %
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to Ph Eur, BP, USP, FCC, JP.
          Global Trade Item Number
          Catalogue Number GTIN
          5002991000 04065273107999
          5002999020 04022536722382

          Documentation

          Material Qualification Dossier

          TitleVersion
          6.1

          Quality Management Dossier (Open Access)

          Title

          Operational Excellence Dossier

          Title

          Nicotinamide SDS

          Title

          Safety Data Sheet (SDS) 

          Nicotinamide Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          5002991000 Plastic bottlePDF Specification Document
          5002999020 Fibre cartonPDF Specification Document

          Certificates

          Title