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DEFB105A

defensin, beta 105A

Synonyms:
BD-5, DEFB-5, DEFB105
Species:
Human DEFB105A (245908), dog DEFB105A (100306932)
UniProtKB ID:
Q8NG35, A1A581, Q8IZN8
Gene ID:
  • Human(245908) Summary: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105A, represents the more centromeric copy. [provided by RefSeq, Jul 2008]
  • dog(100306932) defensin, beta 105A

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