361547 GSK-3β Inhibitor VI - CAS 62673-69-2 - Calbiochem

361547
Wyświetl ceny i dostępność

Przegląd

Replacement Information

Tabela kluczowych gatunków

Empirical FormulaCAS #
C₆H₃Br₂ClOS 62673-69-2

Ceny i dostępność

Numer katalogowy DostępnośćOpakowanie Ilość/opak. Cena netto Ilość
361547-5MG
Pobieram informacje o dostępności...
Niedostępny w magazynie PLNiedostępny w magazynie PL
Dostępny w magazynie 
Wycofano
Dostępna ograniczona ilość
Dostępność będzie potwierdzona
    Remaining : Will advise
      Remaining : Will advise
      Doradzimy
      Skontaktuj się z Zespołem Obsługi Klienta
      Contact Customer Service

      Ampulka plastikowa 5 mg
      Pobieranie ceny...
      Nie udało się pobrać ceny
      Minimum Quantity needs to be mulitiple of
      Na zapytanie Więcej informacji
      Zapisano ()
       
      Poproś o podanie ceny netto
      Description
      OverviewA thienyl α-chloromethyl ketone compound that acts as a cell-permeable, irreversible, and non-ATP competitive inhibitor of GSK-3β (IC50 = 1 µM). This reactive alkylating agent is selective towards GSK-3β and does not affect PKA activity even at concentrations as high as 100 µM.
      Catalogue Number361547
      Brand Family Calbiochem®
      Synonyms2-Chloro-1-(4,5-dibromo-thiophen-2-yl)-ethanone
      References
      ReferencesConde, S., et al. 2003. J. Med. Chem. 46, 4631.
      Product Information
      CAS number62673-69-2
      ATP CompetitiveN
      FormOrange solid
      Hill FormulaC₆H₃Br₂ClOS
      Chemical formulaC₆H₃Br₂ClOS
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGsk-3β
      Primary Target IC<sub>50</sub>1 µM against Gsk-3β
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution in DMSO, aliquot and freeze (-20°). DMSO stock solutions are stable for up to 1 week at -20°C. For increased stability reconstitute in chloroform, aliquot, dry under a stream of inert gas, and freeze (-20°C). Reconstitute in fresh DMSO just prior to use.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      GSK-3β Inhibitor VI - CAS 62673-69-2 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      GSK-3β Inhibitor VI - CAS 62673-69-2 - Calbiochem Certificates of Analysis

      TitleLot Number
      361547

      References

      Przegląd literatury
      Conde, S., et al. 2003. J. Med. Chem. 46, 4631.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-April-2011 RFH
      Synonyms2-Chloro-1-(4,5-dibromo-thiophen-2-yl)-ethanone
      DescriptionA cell-permeable, and non-ATP competitive inhibitor of GSK-3β (IC50 = 1 µM). This reactive alkylating agent is selective towards GSK-3β and does not affect PKA activity even at concentrations as high as 100 µM.
      FormOrange solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number62673-69-2
      Chemical formulaC₆H₃Br₂ClOS
      Structure formulaStructure formula
      Purity≥90% by HPLC
      SolubilityDMSO (5 mg/ml) or Ethanol (1 mg/ml). Use fresh, anhydrous DMSO only.
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution in DMSO, aliquot and freeze (-20°). DMSO stock solutions are stable for up to 1 week at -20°C. For increased stability reconstitute in chloroform, aliquot, dry under a stream of inert gas, and freeze (-20°C). Reconstitute in fresh DMSO just prior to use.
      Toxicity Standard Handling
      ReferencesConde, S., et al. 2003. J. Med. Chem. 46, 4631.