400052 Hygromycin B, Streptomyces sp., Sterile-Filtered Solution in PBS, Cell Culture-Tested - CAS 31282-04-9 - Calbiochem

Przegląd

Replacement Information

Tabela kluczowych gatunków

Empirical FormulaCAS #
C₂₀H₃₇N₃O₁₃ 31282-04-9

Ceny i dostępność

Numer katalogowy DostępnośćOpakowanie Ilość/opak. Cena netto Ilość
400052-20ML
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      400052-50ML
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      Niedostępny w magazynie PLNiedostępny w magazynie PL
      Dostępny w magazynie 
      Wycofano
      Dostępna ograniczona ilość
      Dostępność będzie potwierdzona
        Remaining : Will advise
          Remaining : Will advise
          Doradzimy
          Skontaktuj się z Zespołem Obsługi Klienta
          Contact Customer Service

          Beben aluminiowy 50 ml
          Pobieranie ceny...
          Nie udało się pobrać ceny
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          Description
          OverviewSterile liquid formulation of Cat. No. 400050.
          Catalogue Number400052
          Brand Family Calbiochem®
          References
          ReferencesSugimoto, K., et al. 1994. Plant J. 5, 863.
          Lee, M.G., and van der Ploeg, L.H. 1991. Gene 105, 255.
          Salauze, D., et al. 1990. Antimicrob. Agents Chemother. 34, 1915.
          Cullen, D., et al. 1987. Gene 57, 21.
          Rao, S.N., et al. 1983. Antimicrob. Agents Chemother. 24, 689.
          Santerre, R.F., et al. 1984. Gene 30, 147.
          Gonzalez, A., et al. 1978. Biochim. Biophys. Acta 521, 459.
          Product Information
          CAS number31282-04-9
          FormLiquid
          Formulation50 mg/ml active antibiotic in sterile-filtered PBS, pH 7.2.
          Hill FormulaC₂₀H₃₇N₃O₁₃
          Chemical formulaC₂₀H₃₇N₃O₁₃
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          ApplicationHygromycin B is an aminoglycoside antibiotic that inhibits the growth of prokaryotic and eukaryotic microorganisms and mammalian cells. Inhibits protein synthesis by interfering with the translocation of the 70S ribosome and causes misreading of mRNA.
          Biological Information
          Biological activityPotency: ≥1000 U/mg
          Purity≥85% by HPLC and TLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSWK2130000
          Safety Information
          R PhraseR: 26/27/28-37/38-41

          Very toxic by inhalation, in contact with skin and if swallowed.
          Irritating to respiratory system and skin.
          Risk of serious damage to eyes.
          S PhraseS: 23-26-36/37/39-45

          Do not breathe fumes.
          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Highly Toxic & Carcinogenic / Teratogenic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Hygromycin B, Streptomyces sp., Sterile-Filtered Solution in PBS, Cell Culture-Tested - CAS 31282-04-9 - Calbiochem MSDS

          Title

          Safety Data Sheet (SDS) 

          Hygromycin B, Streptomyces sp., Sterile-Filtered Solution in PBS, Cell Culture-Tested - CAS 31282-04-9 - Calbiochem Certificates of Analysis

          TitleLot Number
          400052

          References

          Przegląd literatury
          Sugimoto, K., et al. 1994. Plant J. 5, 863.
          Lee, M.G., and van der Ploeg, L.H. 1991. Gene 105, 255.
          Salauze, D., et al. 1990. Antimicrob. Agents Chemother. 34, 1915.
          Cullen, D., et al. 1987. Gene 57, 21.
          Rao, S.N., et al. 1983. Antimicrob. Agents Chemother. 24, 689.
          Santerre, R.F., et al. 1984. Gene 30, 147.
          Gonzalez, A., et al. 1978. Biochim. Biophys. Acta 521, 459.

          Brochure

          Title
          Antibiotics Profiler
          The Complete Molecular Biology Toolkit - Expert workflow solutions from DNA cloning to protein expression
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision04-October-2007 RFH
          DescriptionHygromycin B is an aminoglycoside antibiotic that inhibits the growth of prokaryotic and eukaryotic microorganisms and mammalian cells. Inhibits protein synthesis by interfering with the translocation of the 70S ribosome and causes misreading of mRNA. Resistance to hygromycin B is conferred by a gene whose product, hygromycin B phospho-transferase that phosphorylates and inactivates the drug. Hygromycin B has been used to select mutants carrying the hygromycin B resistance gene in a wide variety of cells including bacterial, protozoal, yeast, fungal, plant, and mammalian cells. Typical concentrations used for mammalian cell selection are between 0.05 to 1 mg/ml. The appropriate concentration for use must be determined empirically for each cell type.
          FormLiquid
          Formulation50 mg/ml active antibiotic in sterile-filtered PBS, pH 7.2.
          CAS number31282-04-9
          RTECSWK2130000
          Chemical formulaC₂₀H₃₇N₃O₁₃
          Structure formulaStructure formula
          Purity≥85% by HPLC and TLC
          Biological activityPotency: ≥1000 U/mg
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Toxicity Highly Toxic & Carcinogenic / Teratogenic
          Merck USA index14, 4852
          ReferencesSugimoto, K., et al. 1994. Plant J. 5, 863.
          Lee, M.G., and van der Ploeg, L.H. 1991. Gene 105, 255.
          Salauze, D., et al. 1990. Antimicrob. Agents Chemother. 34, 1915.
          Cullen, D., et al. 1987. Gene 57, 21.
          Rao, S.N., et al. 1983. Antimicrob. Agents Chemother. 24, 689.
          Santerre, R.F., et al. 1984. Gene 30, 147.
          Gonzalez, A., et al. 1978. Biochim. Biophys. Acta 521, 459.

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          Kategorie

          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Antibiotics > Antimicrobial Agents
          Life Science Research > Cell Culture and Systems > Antibiotics & Selection Agents