422686 Kininogen, High Molecular Weight, Single Chain, Human Plasma - Calbiochem

422686
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422686-1MG
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      Description
      OverviewNative, single chain, high molecular weight Kininogen from human plasma. Nonenzymatic cofactor of the contact activation system. Links prekallikrein to negatively charged surfaces, thereby allowing activation to kallikrein by surface-bound Factor α-XIIa. Also circulates in plasma in complex with Factor XI and may play a role in the activation of Factor XI to Factor XIa by Factor α-XIIa. Serves as a source of bradykinin, a potent vasoactive peptide important in hypotension studies.
      Catalogue Number422686
      Brand Family Calbiochem®
      References
      ReferencesWeisel, J.W., et al. 1994. J. Biol. Chem. 269, 10100.
      Product Information
      FormLiquid
      FormulationIn 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Kininogen, High Molecular Weight, Single Chain, Human Plasma - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      Kininogen, High Molecular Weight, Single Chain, Human Plasma - Calbiochem Certificates of Analysis

      TitleLot Number
      422686

      References

      Przegląd literatury
      Weisel, J.W., et al. 1994. J. Biol. Chem. 269, 10100.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-August-2008 RFH
      DescriptionNative, single chain, high molecular weight Kininogen from human plasma. Non-enzymatic cofactor of the contact activation system. Links prekallikrein to negatively charged surfaces, thereby allowing activation to kallikrein by surface-bound Factor a-XIIa. Also circulates in plasma in complex with Factor XI, that may play a role in the activation of Factor XI to Factor XIa by Factor α-XIIa. Serves as a source of bradykinin, a potent vasoactive peptide important in hypotension studies.
      FormLiquid
      FormulationIn 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
      Concentration Label Please refer to vial label for lot-specific concentration
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥95% by SDS-PAGE
      Storage ≤ -70°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesWeisel, J.W., et al. 1994. J. Biol. Chem. 269, 10100.