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219384 Anti-Cathepsin S Rabbit pAb

219384
  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
HRbPolyclonal Antibody
Description
Overview

This product has been discontinued.



Recognizes the ~37 kDa latent and the ~28 kDa active forms of cathepsin S in human tumors.

Catalogue Number219384
Brand Family Calbiochem®
References
ReferencesShi, Guo-Ping, et al. 1992. J. Biol. Chem. 267, 7258.
Wiederanders, B. et al. 1992. J. Biol. Chem. 269, 13708.
Chauhan, S.S., et al. 1991. Cancer Res. 51, 1487.
Kane, S.E. and Gottesman, M.M. 1990. In Seminars in Cancer Biology, ed, M.M. Gottesman, Vol 1; 137-152.
Barrett, A., et al. 1981. Meth. Enzymol. 80, 535.
Kane, S.E. and Gottesman, M.M. 1990. In Seminars in Cancer Biology, ed., M.M. Gottesman, Vol1; 137-152.
Chauhan, S.S., et al. 1991. Cancer Res. 51, 1487.
Product Information
FormLiquid
FormulationUndiluted serum.
Preservative≤0.1% sodium azide
Quality LevelMQ100
Applications
Key Applications Immunoblotting (Western Blotting)
Application NotesImmunoblotting (1:1000-1:2000, colorimetric)
Application CommentsVariables associated with assay conditions will dictate the optimal working dilution.
Biological Information
Immunogenrecombinant, human cathepsin S fused to maltose binding protein and expressed in E. coli
ImmunogenHuman
HostRabbit
IsotypeIgG
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Anti-Cathepsin S Rabbit pAb SDS

Title

Safety Data Sheet (SDS) 

Anti-Cathepsin S Rabbit pAb Certificates of Analysis

TitleLot Number
219384

References

Reference overview
Shi, Guo-Ping, et al. 1992. J. Biol. Chem. 267, 7258.
Wiederanders, B. et al. 1992. J. Biol. Chem. 269, 13708.
Chauhan, S.S., et al. 1991. Cancer Res. 51, 1487.
Kane, S.E. and Gottesman, M.M. 1990. In Seminars in Cancer Biology, ed, M.M. Gottesman, Vol 1; 137-152.
Barrett, A., et al. 1981. Meth. Enzymol. 80, 535.
Kane, S.E. and Gottesman, M.M. 1990. In Seminars in Cancer Biology, ed., M.M. Gottesman, Vol1; 137-152.
Chauhan, S.S., et al. 1991. Cancer Res. 51, 1487.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision25-July-2007 RFH
ApplicationImmunoblotting (1:1000-1:2000, colorimetric)
DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~37 kDa latent and the ~28 kDa active forms of cathepsin S.
BackgroundCathepsin S is a cysteine proteinase expressed in a variety of cells. The latent pro-cathepsin S (37 kDa) is processed to the active single chain form (28 kDa). Unlike cathepsin B and cathepsin L, cathepsin S exists only in single chain form. The pro peptide contains 99 amino acids. Mature Cathepsin S is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. High levels of cathepsin S expression have been demonstrated for many human tumors including cancers of the kidney, lung, colon, breast and ovary.
HostRabbit
Immunogen speciesHuman
Immunogenrecombinant, human cathepsin S fused to maltose binding protein and expressed in E. coli
IsotypeIgG
Specieshuman
FormLiquid
FormulationUndiluted serum.
Preservative≤0.1% sodium azide
CommentsVariables associated with assay conditions will dictate the optimal working dilution.
Storage -20°C
Avoid freeze/thaw
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesShi, Guo-Ping, et al. 1992. J. Biol. Chem. 267, 7258.
Wiederanders, B. et al. 1992. J. Biol. Chem. 269, 13708.
Chauhan, S.S., et al. 1991. Cancer Res. 51, 1487.
Kane, S.E. and Gottesman, M.M. 1990. In Seminars in Cancer Biology, ed, M.M. Gottesman, Vol 1; 137-152.
Barrett, A., et al. 1981. Meth. Enzymol. 80, 535.
Kane, S.E. and Gottesman, M.M. 1990. In Seminars in Cancer Biology, ed., M.M. Gottesman, Vol1; 137-152.
Chauhan, S.S., et al. 1991. Cancer Res. 51, 1487.