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05-23-0150 [Arg⁸]-Vasopressin

05-23-0150
  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
OverviewSynthetic [Arg8]-Vasopressin. An antidiuretic peptide hormone. Released from the hypothalamus during stress. Although noted primarily for its hemodynamic and hemostatic properties, it appears to affect the immune system. Acts via the activation of the adenylate cyclase system resulting in increased cAMP levels (EC50 = 34 nM). Reported to induce an increase in [Ca2+]i in hippocampal neurons via action of VI vasopressin receptors coupled with N-type Ca2+ channels.
Catalogue Number05-23-0150
Brand Family Calbiochem®
SynonymsAVP
References
ReferencesMihara, T., et al. 1999. Brain Res. Bull. 49, 343.
Kobayashi, H., et al. 1994. Brain Res. 647, 145.
Monaghan, M.L., et al. 1993. Gen. Pharmacol. 24, 1013.
Product Information
CAS number113-79-1
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₄₆H₆₅N₁₅O₁₂S₂
Chemical formulaC₄₆H₆₅N₁₅O₁₂S₂
Sold on the basis of peptide contentY
Applications
Biological Information
Purity≥97% by HPLC
Physicochemical Information
Peptide ContentY
Peptide SequenceH-Cys¹-Tyr-Phe-Gln-Asn-Cys⁶-Pro-Arg-Gly-NH₂ (disulfide bond: 1 → 6)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20

Harmful by inhalation.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

[Arg⁸]-Vasopressin Certificates of Analysis

TitleLot Number
05-23-0150

References

Reference overview
Mihara, T., et al. 1999. Brain Res. Bull. 49, 343.
Kobayashi, H., et al. 1994. Brain Res. 647, 145.
Monaghan, M.L., et al. 1993. Gen. Pharmacol. 24, 1013.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-August-2008 JSW
SynonymsAVP
DescriptionSynthetic [Arg8]-Vasopressin. An anti-diuretic peptide hormone. Released from the hypothalamus during stress. Although noted primarily for its hemodynamic and hemostatic properties, it appears to affect the immune system. Acts via the activation of the adenylate cyclase system resulting in increased cAMP levels (EC50 = 34 nM).
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
CAS number113-79-1
Chemical formulaC₄₆H₆₅N₁₅O₁₂S₂
Peptide SequenceH-Cys¹-Tyr-Phe-Gln-Asn-Cys⁶-Pro-Arg-Gly-NH₂ (disulfide bond: 1 → 6)
Purity≥97% by HPLC
SolubilityH₂O (1 mg/ml)
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Harmful
Merck USA index14 9938
ReferencesMihara, T., et al. 1999. Brain Res. Bull. 49, 343.
Kobayashi, H., et al. 1994. Brain Res. 647, 145.
Monaghan, M.L., et al. 1993. Gen. Pharmacol. 24, 1013.