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05-23-0301 Atrial Natriuretic Factor 1-28, Rat

05-23-0301
  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₁₂₈H₂₀₅N₄₅O₃₉S₂88898-17-3
Description
OverviewReduces the activity of Na+,K+-ATPase in rat kidney. Activator of neuronal guanylate cyclase. Suppresses the transcription of its own guanylyl cyclase-linked receptor.
Catalogue Number05-23-0301
Brand Family Calbiochem®
SynonymsrANF, SLRRSSCFGGRIDRIGAQSGLGCNSFRY
References
ReferencesCao, L., et al. 1995. J. Biol. Chem. 270, 24891. Gorny, D., et al. 1994. J. Physiol. Pharmacol. 45, 173. Rambotti, M.G., et al. 1994. Brain Res. 644, 52. Spreca, A., et al. 1994. Histochem. J. 26, 778.
Product Information
CAS number88898-17-3
FormWhite to off-white solid
Hill FormulaC₁₂₈H₂₀₅N₄₅O₃₉S₂
Chemical formulaC₁₂₈H₂₀₅N₄₅O₃₉S₂
Hygroscopic Hygroscopic
Sold on the basis of peptide contentY
Applications
Biological Information
Purity≥97% by HPLC
Physicochemical Information
Peptide ContentY
Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Atrial Natriuretic Factor 1-28, Rat Certificates of Analysis

TitleLot Number
05-23-0301

References

Reference overview
Cao, L., et al. 1995. J. Biol. Chem. 270, 24891. Gorny, D., et al. 1994. J. Physiol. Pharmacol. 45, 173. Rambotti, M.G., et al. 1994. Brain Res. 644, 52. Spreca, A., et al. 1994. Histochem. J. 26, 778.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-September-2008 RFH
SynonymsrANF, SLRRSSCFGGRIDRIGAQSGLGCNSFRY
DescriptionReduces the activity of Na+-K+-ATPase in rat kidney. Activator of neuronal guanylate cyclase. Suppresses the transcription of its own guanylyl cyclase-linked receptor.
FormWhite to off-white solid
CAS number88898-17-3
Chemical formulaC₁₂₈H₂₀₅N₄₅O₃₉S₂
Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
Purity≥97% by HPLC
Solubility5% Acetic acid (1 mg/ml) or DMSO (5 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
Merck USA index14, 1360
ReferencesCao, L., et al. 1995. J. Biol. Chem. 270, 24891. Gorny, D., et al. 1994. J. Physiol. Pharmacol. 45, 173. Rambotti, M.G., et al. 1994. Brain Res. 644, 52. Spreca, A., et al. 1994. Histochem. J. 26, 778.