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203410 BLEOCIN™ Streptomyces verticillus, Sterile-Filtered, Aqueous Solution - CAS 55658-47-4 - Calbiochem

203410
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Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₅₇H₈₉CuN₁₉O₂₁S₂·3HCl55658-47-4

Products

Catalogue NumberPackaging Qty/Pack
203410-10ML Plastic ampoule 10 ml
Description
OverviewA unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ Antibiotic cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker.
Catalogue Number203410
Brand Family Calbiochem®
References
ReferencesSergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
Mulsant, P., et al. 1988. Somat. Cell Mol. Genet. 14, 243.
Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
Takita, T., et al. 1972. J. Antibiot. 25, 755.
Product Information
CAS number55658-47-4
FormLiquid
FormulationSterile-filtered solution supplied at 20 mg/ml in H₂O.
Hill FormulaC₅₇H₈₉CuN₁₉O₂₁S₂·3HCl
Chemical formulaC₅₇H₈₉CuN₁₉O₂₁S₂·3HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSEC5990700
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

BLEOCIN™ Streptomyces verticillus, Sterile-Filtered, Aqueous Solution - CAS 55658-47-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

BLEOCIN™ Streptomyces verticillus, Sterile-Filtered, Aqueous Solution - CAS 55658-47-4 - Calbiochem Certificates of Analysis

TitleLot Number
203410

References

Reference overview
Sergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
Mulsant, P., et al. 1988. Somat. Cell Mol. Genet. 14, 243.
Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
Takita, T., et al. 1972. J. Antibiot. 25, 755.

Brochure

Title
Antibiotics Profiler
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-July-2007 DCH
DescriptionA unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker.
FormLiquid
FormulationSterile-filtered solution supplied at 20 mg/ml in H₂O.
CAS number55658-47-4
RTECSEC5990700
Chemical formulaC₅₇H₈₉CuN₁₉O₂₁S₂·3HCl
Structure formulaStructure formula
Storage -20°C
Avoid freeze/thaw
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Harmful & Carcinogenic / Teratogenic
Merck USA index14, 1318
ReferencesSergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
Mulsant, P., et al. 1988. Somat. Cell Mol. Genet. 14, 243.
Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931.
Takita, T., et al. 1972. J. Antibiot. 25, 755.