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217588 CD40-Fc Fusion Protein, Human, Recombinant, CHO Cells

217588
  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Overview

This product has been discontinued.





Recombinant, human CD40 (193 amino acids extracellular domain) fused to murine IgG2a Fc (233 amino acids) and expressed in NSO cells. Member of the TNF receptor family. Present on all B cells except plasma cells and on some epithelial cells, carcinomas, and lymphoid dendritic cells. Interaction with its ligand, CD154 (CD40 ligand) is important for isotype switching. Plays an important role in B cell activation.
Catalogue Number217588
Brand Family Calbiochem®
References
ReferencesHermann, P., et al. 1993. Eur. J. Immunol. 23, 961.
Armitage, R.J., et al. 1992. Eur. J. Immunol. 22, 2071.
Product Information
FormLiquid
FormulationIn 150 mM NaCl, 100 mM KCl, 50 mM sodium phosphate, 0.5 mg/ml gentamicin sulfate buffer, pH 7.5.
Applications
Biological Information
Purity≥95% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial use, aliquot and freeze (-20°C) for long-term storage.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

CD40-Fc Fusion Protein, Human, Recombinant, CHO Cells Certificates of Analysis

TitleLot Number
217588

References

Reference overview
Hermann, P., et al. 1993. Eur. J. Immunol. 23, 961.
Armitage, R.J., et al. 1992. Eur. J. Immunol. 22, 2071.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision03-June-2008 RFH
DescriptionRecombinant, human CD40 (193 amino acids extracellular domain) fused to murine IgG2a Fc (233 amino acids) and expressed in NSO cells. Member of the TNF receptor family. Present on all B cells except plasma cells and on some epithelial cells, carcinomas, and lymphoid dendritic cells. Interaction with its ligand, CD154 (CD40 ligand) is important for isotype switching. Plays an important role in B cell activation.
FormLiquid
FormulationIn 150 mM NaCl, 100 mM KCl, 50 mM sodium phosphate, 0.5 mg/ml gentamicin sulfate buffer, pH 7.5.
Concentration Label Please refer to vial label for lot-specific concentration
Purity≥95% by SDS-PAGE
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial use, aliquot and freeze (-20°C) for long-term storage.
Toxicity Standard Handling
ReferencesHermann, P., et al. 1993. Eur. J. Immunol. 23, 961.
Armitage, R.J., et al. 1992. Eur. J. Immunol. 22, 2071.