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03-32-5032 MMP-2/MMP-7 Substrate, Fluorogenic - Calbiochem

03-32-5032
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Products

Catalogue NumberPackaging Qty/Pack
03-32-5032-1MG Plastic ampoule 1 mg
Description
OverviewExtremely sensitive fluorogenic substrate for matrix metalloproteinases (MMPs). Suitable for assessment of total activity in crude preparations by continuous assays (kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M-1sec-1 for MMP-2).
Catalogue Number03-32-5032
Brand Family Calbiochem®
References
ReferencesKnight, C.G., et al. 1992. FEBS Lett. 296, 263.
Product Information
ATP CompetitiveN
FormYellow solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₄₉H₆₈N₁₄O₁₅
Chemical formulaC₄₉H₆₈N₁₄O₁₅
ReversibleN
Quality LevelMQ200
Applications
Biological Information
Primary TargetFluorogenic substrate for matrix metalloproteinases (MMPs)
Primary Target IC<sub>50</sub>kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M⁻¹ sec⁻¹ for MMP-2
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide SequenceMCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH₂ ·TFA [Dpa = N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl]
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

MMP-2/MMP-7 Substrate, Fluorogenic - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

MMP-2/MMP-7 Substrate, Fluorogenic - Calbiochem Certificates of Analysis

TitleLot Number
03-32-5032

References

Reference overview
Knight, C.G., et al. 1992. FEBS Lett. 296, 263.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision21-June-2013 JSW
DescriptionExtremely sensitive fluorogenic substrate for matrix metalloproteinases (MMPs; excitation maximum: 325 nm; emission maximum: 393 nm). Suitable for assessment of total activity in crude preparations by continuous assays (kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M-1sec-1 for MMP-2).
FormYellow solid
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₄₉H₆₈N₁₄O₁₅
Peptide SequenceMCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH₂ ·TFA [Dpa = N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl]
Purity≥95% by HPLC
Solubility20% Acetic Acid (1 mg/ml)
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesKnight, C.G., et al. 1992. FEBS Lett. 296, 263.