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05-23-0701 Neurokinin A - CAS 86933-74-6 - Calbiochem

05-23-0701
  
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Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₅₀H₈₀N₁₄O₁₄S86933-74-6
Description
OverviewPeptide belonging to the tachykinin family. A more potent bronchioconstrictor than substance P. May be released in association with the activation of polymodal C-nociceptors. May regulate neutrophil recruitment into lower respiratory tract. Exhibits higher affinity for NK-2 receptors compared to NK-1 or NK-3 and plays a role in hematopoietic regulation.
Catalogue Number05-23-0701
Brand Family Calbiochem®
SynonymsNKA, HKTDSFVGLM-NH₂, Substance K, Neuromedin L
References
ReferencesRameshwar, P., and Gascom, P. 1996. Blood 88, 98.
Chan, C.C., et al. 1993. Can. J. Physiol. Pharmacol. 72, 11.
Nagahisa, A., et al. 1992. Eur. J. Pharmacol. 217, 191.
von Essen, S.G., et al. 1992. Am. J. Physiol. 263, L226.
Xu, X.J., and Wiesenfeld-Hallin, A. 1992. Acta Physiol. Scand. 144, 63.
Product Information
CAS number86933-74-6
FormWhite to off-white solid
FormulationSupplied as an trifluoroacetate salt.
Hill FormulaC₅₀H₈₀N₁₄O₁₄S
Chemical formulaC₅₀H₈₀N₁₄O₁₄S
Hygroscopic Hygroscopic
Sold on the basis of peptide contentY
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Peptide ContentY
Peptide SequenceH-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Neurokinin A - CAS 86933-74-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Neurokinin A - CAS 86933-74-6 - Calbiochem Certificates of Analysis

TitleLot Number
05-23-0701

References

Reference overview
Rameshwar, P., and Gascom, P. 1996. Blood 88, 98.
Chan, C.C., et al. 1993. Can. J. Physiol. Pharmacol. 72, 11.
Nagahisa, A., et al. 1992. Eur. J. Pharmacol. 217, 191.
von Essen, S.G., et al. 1992. Am. J. Physiol. 263, L226.
Xu, X.J., and Wiesenfeld-Hallin, A. 1992. Acta Physiol. Scand. 144, 63.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-September-2008 RFH
SynonymsNKA, HKTDSFVGLM-NH₂, Substance K, Neuromedin L
DescriptionPeptide belonging to the tachykinin family. A more potent bronchio-constrictor than substance P. May be released in association with the activation of polymodal c-nociceptors. May regulate neutrophil recruitment into lower respiratory tract. Exhibits higher affinity for NK-2 receptors compared to NK-1 or NK-3 and plays a role in hematopoietic regulation.
FormWhite to off-white solid
FormulationSupplied as an trifluoroacetate salt.
CAS number86933-74-6
Chemical formulaC₅₀H₈₀N₁₄O₁₄S
Peptide SequenceH-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH₂
Purity≥95% by HPLC
Solubility5% Acetic Acid (1 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Harmful
ReferencesRameshwar, P., and Gascom, P. 1996. Blood 88, 98.
Chan, C.C., et al. 1993. Can. J. Physiol. Pharmacol. 72, 11.
Nagahisa, A., et al. 1992. Eur. J. Pharmacol. 217, 191.
von Essen, S.G., et al. 1992. Am. J. Physiol. 263, L226.
Xu, X.J., and Wiesenfeld-Hallin, A. 1992. Acta Physiol. Scand. 144, 63.