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05-23-2102 Secretin, Human

05-23-2102
  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
OverviewSynthetic, human secretin. A strongly basic gastrointestinal peptide hormone that stimulates the secretion of bicarbonate-rich pancreatic fluid. Causes a dose-dependent increase in cAMP accumulation in pancreatic duct lines.
Catalogue Number05-23-2102
Brand Family Calbiochem®
References
ReferencesMarino, L.R., and Cotton, C.U. 1996. Am. J. Physiol. 270, G676.
Villanger, O., et al. 1995. Gastroenterology 108, 850.
Product Information
CAS number1393-25-5
FormWhite to off-whit lyophilized solid
FormulationSold on the basis of peptide content.
Hill FormulaC₁₃₀H₂₂₀N₄₄O₄₀
Chemical formulaC₁₃₀H₂₂₀N₄₄O₄₀
Sold on the basis of peptide contentY
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Peptide ContentY
Peptide SequenceH-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSVS4010000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Secretin, Human Certificates of Analysis

TitleLot Number
05-23-2102

References

Reference overview
Marino, L.R., and Cotton, C.U. 1996. Am. J. Physiol. 270, G676.
Villanger, O., et al. 1995. Gastroenterology 108, 850.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-September-2008 RFH
Description

This product has been discontinued.

We apologize for the inconvenience, but we do not currently have an alternative product.






Synthetic, human secretin. A strongly basic gastrointestinal peptide hormone that stimulates the secretion of bicarbonate-rich pancreatic fluid. Causes a dose-dependent increase in cAMP-accumulation in pancreatic duct cell lines (mean effective concentration = 15 nm). Increases plasma membrane chloride permeability.
FormWhite to off-whit lyophilized solid
FormulationSold on the basis of peptide content.
CAS number1393-25-5
RTECSVS4010000
Chemical formulaC₁₃₀H₂₂₀N₄₄O₄₀
Peptide SequenceH-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH₂
Purity≥95% by HPLC
Solubility5% Acetic Acid (1 mg/ml) or H₂O (1 mg/ml)
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
Merck USA index14, 8421
ReferencesMarino, L.R., and Cotton, C.U. 1996. Am. J. Physiol. 270, G676.
Villanger, O., et al. 1995. Gastroenterology 108, 850.