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Merck

MAK085

Lipid Peroxidation (MDA) Assay Kit

sufficient for 100 colorimetric or fluorometric tests

Synonym(s):

MDA Assay, TBARS Assay, Thiobarbituric Acid Reactive Substances Assay

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About This Item

NACRES:
NA.84
UNSPSC Code:
12161503

Product Name

Lipid Peroxidation (MDA) Assay Kit, sufficient for 100 colorimetric or fluorometric tests

usage

sufficient for 100 colorimetric or fluorometric tests

species reactivity

mouse

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

storage condition

dry at room temperature

technique(s)

activity assay: suitable

input

tissue

detection method

colorimetric
fluorometric

relevant disease(s)

endocrinological disorders, diabetes; neurological disorders; cancer; cardiovascular diseases

storage temp.

−20°C

Gene Information

mouse ... Lpolv(100035571)

Application

Lipid peroxidation (MDA) assay kit has been used to determine the levels of malondialdehyde (MDA).
Suitable for the measurement of malondialdehyde (MDA) in a variety of samples including tissue, cells and plasma

Biochem/physiol Actions

In this kit, lipid peroxidation is determined by the reaction of MDA with thiobarbituric acid (TBA) to form a colorimetric (532 nm)/fluorometric (λex = 532/λem = 553 nm) product, proportional to the MDA present.

General description

Lipid peroxidation is the degradation of lipids that occurs as a result of oxidative damage and is a useful marker for oxidative stress. Polyunsaturated lipids are susceptible to an oxidative attack, typically by reactive oxygen species, resulting in a well-defined chain reaction with the production of end products such as malondialdehyde (MDA). Lipid peroxidation may contribute to the pathology of many diseases including atherosclerosis, diabetes, and Alzheimer′s.

flash_point_c

14 °C - closed cup

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1C

Storage Class

3 - Flammable liquids

flash_point_f

57.2 °F - closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
8L03K07390
8A20K07390
8F15K07390
8H25K07390
8C28K07390

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Marco A Perrone et al.
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Cardiovascular diseases (CVDs) are the most frequent causes of death in the world. Inflammation and oxidative damage contribute significantly to the development of atherosclerosis and CVDs. European Food Safety Authority scientific opinion has acknowledged that hydroxytyrosol (3,4-dihydroxyphenylethanol) and derivatives, contained
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