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ABS580 Anti-FSH, β-subunit Antibody

This Anti-FSH, β-subunit Antibody is validated for use in Immunohistochemistry and Activity Assay and ELISA for the detection of FSH, β-subunit.

Anti-FSH, β-subunit Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Signaling Neuroscience Gene Symbol: Fshb UniProt Number: Q60687
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ABS580
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MIHC, ACT, ELISAGtSerumPolyclonal Antibody
      Description
      Catalogue NumberABS580
      DescriptionAnti-FSH, β-subunit Antibody
      Alternate Names
      • Follitropin subunit beta
      • Follicle-stimulating hormone beta subunit
      • FSH-B
      • FSH-beta
      • Follitropin beta chain
      Background InformationFSH-beta is the critical subunit of FSH hormone, also called Follitropin, and several other hormones. The alpha subunits of LH, FSH, TSH and, hCG are identical, however the beta subunits vary determine the interaction with the receptors. The FSH-beta confers the biological specificity for several growth factors including Follitropin, Thyrotropin, Lutropin and Gonadotropin. FSH is involved in follicle and spermatogenesis and is secreted by the anterior pituitary gland. FSH is also expressed by testis, so FSH-beta can be found there as well during development and in adult tissues.
      References
      Product Information
      FormatSerum
      PresentationGoat polyclonal serum without preservatives.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-FSH, β-subunit Antibody is validated for use in Immunohistochemistry and Activity Assay and ELISA for the detection of FSH, β-subunit.
      Key Applications
      • Immunohistochemistry
      • Activity Assay
      • ELISA
      Application NotesActivity Assay Analysis: This antiserum was reported to neutralize FSH-induced osteoclast formation in mouse bone marrow cultures (Zhu, L.L., et al. (2012). PNAS. 109:14574-14579)
      ELISA: This antiserum was reported to detect the immunogen peptide as well as full-lengh FSH by ELISA (Zhu, L.L., et al. (2012). PNAS. 109:14574-14579).
      Biological Information
      ImmunogenLinear peptide corresponding to a 13-amino acid receptor-binding sequence (LVYKDPARPNTQK) of the β-subunit of mouse FSH.
      ConcentrationPlease refer to lot specific datasheet.
      HostGoat
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Fshb
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight15 kDa (calculated); 19 kDa (glycosylated).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human testis and human fallopian tube tissue.

      Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected FSH, β-subunit in human testis and human fallopian tube tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS580 04055977112177