539745 InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II - Calbiochem

539745
  
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      Overview

      Replacement Information

      Key Spec Table

      Description
      OverviewThe InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II consists of 80, well-characterized, cell permeable, potent and reversible protein kinase inhibitors; the majority of which are ATP-competitive. They are supplied in a convenient 96-well plate format at a concentration of 10 mM in DMSO. The inhibitors in this library will be useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications.
      Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.

      Download a list of all inhibitors of library II, including a comprehensive data set.
      Catalogue Number539745
      Brand Family Calbiochem®
      Application Data

      ** Total higher than 80, as some inhibitors target kinases in other branches as well CMGC: Cdk, MAP, GSK3, and CLK Containing Group CAMK: Ca2+/Calmodulin Dependent Protein Kinases AGC: PKA, PKG, and PKC Containing Group CK: Casein Protein Kinases TK: Tyrosine Kinase Group STE: Yeast Sterile Protein Kinases
      References
      Product Information
      Form96-well plate
      FormulationAll of the inhibitors are supplied at a concentration of 10 mM in DMSO (50 µl/well).
      Hygroscopic Hygroscopic
      Applications
      ApplicationThe InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II consists of 80, well-characterized, cell permeable, potent and reversible protein kinase inhibitors.
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Irritant
      Storage ≤ -70°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II - Calbiochem Certificates of Analysis

      TitleLot Number
      539745

      Technical Info

      Title
      Inhibitor Library II-96 List
      Inhibitor Library II-96 SDF

      Citations

      Title
    • Hou, P., et al. 2013. Science 341, 651.
    • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
    • Yinghong Gao, et al. 2013. Biochem. J. in press.
    • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
    • Cohen, T., et al. 2012. Biochem. J. in press.
    • Elkaim, J., 2012. Biochem. J. in press.
    • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
    • Lee, A.J., et al. 2011. Cancer Res. 71, 1858.
    • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
    • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
    • Donovi, D., et al. 2010 Biochem Soc Trans. 38, 1067.
    • Hooper, S., et al. 2010. British Journal of Cancer 102, 392.
    • Gronenberg, L.S., and Kahne, d., 2009. J. Am. Chem. Soc. 10.1021/ja910361r
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-September-2012 JSW
      Application Data

      ** Total higher than 80, as some inhibitors target kinases in other branches as well CMGC: Cdk, MAP, GSK3, and CLK Containing Group CAMK: Ca2+/Calmodulin Dependent Protein Kinases AGC: PKA, PKG, and PKC Containing Group CK: Casein Protein Kinases TK: Tyrosine Kinase Group STE: Yeast Sterile Protein Kinases
      DescriptionThe InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II consists of 80, well-characterized protein kinase inhibitors, the majority of which are cell-permeable and ATP-competitive. The library is useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications. Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.
      Form96-well plate
      FormulationAll of the inhibitors are supplied at a concentration of 10 mM in DMSO (50 µl/well).
      Intert gas (Yes/No) Packaged under inert gas
      Storage ≤ -70°C
      Hygroscopic
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
      Toxicity Irritant
      Citation
    • Hou, P., et al. 2013. Science 341, 651.
    • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
    • Yinghong Gao, et al. 2013. Biochem. J. in press.
    • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
    • Cohen, T., et al. 2012. Biochem. J. in press.
    • Elkaim, J., 2012. Biochem. J. in press.
    • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
    • Lee, A.J., et al. 2011. Cancer Res. 71, 1858.
    • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
    • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
    • Donovi, D., et al. 2010 Biochem Soc Trans. 38, 1067.
    • Hooper, S., et al. 2010. British Journal of Cancer 102, 392.
    • Gronenberg, L.S., and Kahne, d., 2009. J. Am. Chem. Soc. 10.1021/ja910361r