539746 InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library III - Calbiochem

539746
  
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      Overview

      Replacement Information

      Key Spec Table

      Description
      Overview

      This product has been discontinued.



      The InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library III consists of 84, well-characterized protein kinase inhibitors, the majority of which are cell-permeable and ATP-competitive. This serine/threonine-selective library will be useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications.

      Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.

      Download a list of all inhibitors of library III, including a comprehensive data set.
      Catalogue Number539746
      Brand Family Calbiochem®
      Application Data

      ** Total higher than 84, as some inhibitors target kinases in other branches as well AGC: PKA, PKG, and PKC Containing Group TKL: Tyrosine Kinase-Like Group CMGC: Cdk, MAP, GSK-3, and CLK Containing Group CAMK: Ca2+/Calmodulin Dependent Protein Kinases STE: Yeast Sterile Protein Kinases TK: Tyrosine Kinase
      References
      Product Information
      Form96-well plate
      Formulation81 inhibitors are supplied at a concentration of 10 mM and 3 inhibitors are supplied at a concentration of 5 mM in DMSO (50 µl/well).
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      S PhraseS: 26

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Irritant
      Storage ≤ -70°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library III - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library III - Calbiochem Certificates of Analysis

      TitleLot Number
      539746

      Technical Info

      Title
      Inhibitor Library III-96 List
      Inhibitor Library III-96 SDF

      Citations

      Title
    • Hou, P., et al. 2013. Science 341, 651.
    • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
    • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
    • Cohen, T., et al. 2012. Biochem. J. in press.
    • Elkaim, J., 2012. Biochem. J. in press.
    • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
    • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
    • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
    • Gronenberg, L.S., and Kahne, d., 2009. J. AM. CHEM. SOC. 10.1021/ja910361r
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-September-2012 JSW
      Application Data

      ** Total higher than 84, as some inhibitors target kinases in other branches as well AGC: PKA, PKG, and PKC Containing Group TKL: Tyrosine Kinase-Like Group CMGC: Cdk, MAP, GSK-3, and CLK Containing Group CAMK: Ca2+/Calmodulin Dependent Protein Kinases STE: Yeast Sterile Protein Kinases TK: Tyrosine Kinase
      DescriptionThe InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library III consists of 84 well-characterized protein kinase inhibitors, the majority of which are cell-permeable and ATP-competitive. This serine/threonine-selective library is useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications. Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.
      Form96-well plate
      Formulation81 inhibitors are supplied at a concentration of 10 mM and 3 inhibitors are supplied at a concentration of 5 mM in DMSO (50 µl/well).
      Intert gas (Yes/No) Packaged under inert gas
      Storage ≤ -70°C
      Hygroscopic
      Protect from light
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
      Toxicity Irritant
      Citation
    • Hou, P., et al. 2013. Science 341, 651.
    • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
    • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
    • Cohen, T., et al. 2012. Biochem. J. in press.
    • Elkaim, J., 2012. Biochem. J. in press.
    • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
    • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
    • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
    • Gronenberg, L.S., and Kahne, d., 2009. J. AM. CHEM. SOC. 10.1021/ja910361r