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Merck

MKI1MAG-94K

MILLIPLEX® Mouse Kidney Injury Panel

Configurable Mouse Kidney Injury 6-Plex Panel 1

Synonym(s):

kidney inflammation marker listing, mouse kidney biomarker panel, mouse kidney disease assay, mouse renal damage detection panel, multiplex kidney profiling kit, nephrotoxicity assay overview, renal function biomarker panel, renal injury multiplex kit

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000


Product Name

MILLIPLEX® Mouse Kidney Injury Panel,

Quality Segment

description

Configurable Mouse Kidney Injury 6-Plex Panel 1

species reactivity

mouse

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 73-98%, sensitivity: 0.001-0.041 ng/mL
(MinDC+2SD), standard curve range: 0.001-1 ng/mL
(VEGF), standard curve range: 0.005-5 ng/mL
(IP-10), standard curve range: 0.01-15 ng/mL
(KIM-1), standard curve range: 0.02-25 ng/mL
(TIMP-1), standard curve range: 0.05-50 ng/mL
(β-2-Microglobulin), standard curve range: 0.05-50 ng/mL
(Renin)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Kidney injury can result from various factors including drug toxicity, hypertension, and metabolic disorders. Traditional markers like BUN and creatinine are often insensitive and non-specific. This panel—β-2-Microglobulin, IP-10/CXCL10, KIM-1, Renin, TIMP-1, and VEGF-A—captures key indicators of renal damage, inflammation, and vascular response. The MILLIPLEX® Mouse Kidney Injury Panel 1 enables multiplexed quantification of these biomarkers in mouse urine, serum, or plasma, supporting research in nephrotoxicity, renal disease, and therapeutic development.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes in mouse urine, serum, or plasma samples.

Analytes Included: β-2-Microglobulin, IP-10/CXCL10, KIM-1, Renin, TIMP-1, VEGF-A Note: β-2-Microglobulin and VEGF-A are to be measured in urine samples only.

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:
  • Targets biomarkers involved in renal injury, inflammation, and vascular regulation
  • Includes 6 analytes relevant to nephrotoxicity and kidney function assessment
  • Multiplex format enables simultaneous detection from minimal sample volume Compatible with mouse urine, serum, and plasma samples
  • Designed for research in acute kidney injury, drug-induced nephrotoxicity, and renal disease models
Benefits:
  • Provides a focused profile of kidney injury biomarkers in mouse models
  • Supports investigation of renal damage mechanisms and therapeutic evaluation
  • Facilitates early detection of nephrotoxicity and disease progression
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for preclinical and translational research

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3



Certificates of Analysis (COA)

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