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AP1057 Anti-ANT2 Rabbit pAb

AP1057
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      Rb
      Description
      OverviewRecognizes the ~30 kDa ANT protein in rat liver mitochondria.

      This product has been discontinued.





      Catalogue NumberAP1057
      Brand Family Calbiochem®
      SynonymsAdenine nucleotide translocase
      Application Data
      Detection of human ANT2 by immunoblotting. Samples: whole extract (100 µg) of rat liver mitochondria. Primary antibody: Anti-ANT2 Rabbit pAb (Cat. No. AP1057) (0.25 µg/ml). Detection: chemiluminescence. Data courtesy of Sandra Wiley and Matthew Rardin, University of California San Diego.
      References
      ReferencesLee, J., et al. 2007. Mol. Cell Prot. 4, 669.
      Le Bras, M., et al. 2006. Cancer Res. 18, 9143.
      Loiseau, D., et al. 2002. Exp. Cell Res. 1, 12.
      Product Information
      FormLiquid
      FormulationIn PBS.
      Positive controlRat liver mitochondria
      Preservative≤0.1% sodium azide
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (0.25 µg/ml)
      Application CommentsAntibody should be titrated for optimal results in individual systems.
      Biological Information
      Immunogena synthetic peptide corresponding to amino acids surrounding Ser⁵² of human ANT2
      ImmunogenHuman
      HostRabbit
      IsotypeIgG
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-ANT2 Rabbit pAb MSDS

      Title

      Safety Data Sheet (SDS) 

      Anti-ANT2 Rabbit pAb Certificates of Analysis

      TitleLot Number
      AP1057

      References

      Reference overview
      Lee, J., et al. 2007. Mol. Cell Prot. 4, 669.
      Le Bras, M., et al. 2006. Cancer Res. 18, 9143.
      Loiseau, D., et al. 2002. Exp. Cell Res. 1, 12.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-October-2011 JSW
      SynonymsAdenine nucleotide translocase
      ApplicationImmunoblotting (0.25 µg/ml)
      Application Data
      Detection of human ANT2 by immunoblotting. Samples: whole extract (100 µg) of rat liver mitochondria. Primary antibody: Anti-ANT2 Rabbit pAb (Cat. No. AP1057) (0.25 µg/ml). Detection: chemiluminescence. Data courtesy of Sandra Wiley and Matthew Rardin, University of California San Diego.
      DescriptionImmunoaffinity purified rabbit polyclonal antibody. Recognizes the ~30 kDa ANT2 protein.
      BackgroundAdenine nucleotide translocase (ANT) mediates the exchange of ADP and ATP on the inner mitochondrial membrane of cells. There are four ANT proteins present in humans (ANT1-ANT4) encoded by closely related genes that belong to the mitochondrial carrier family. The ANT isoforms are expressed in a tissue- and developmental-specific manner. ANT is reported to be a major component of the permeability transition pore (PTP) that can mediate mitochodrial membrane polarization (MMP) and cell death of cancer cells. Purified ANT inserted into membranes can form nonspecific pores in response to multiple proapoptotic compounds.
      HostRabbit
      Immunogen speciesHuman
      Immunogena synthetic peptide corresponding to amino acids surrounding Ser⁵² of human ANT2
      IsotypeIgG
      Specieshuman, mouse, rat
      Positive controlRat liver mitochondria
      FormLiquid
      FormulationIn PBS.
      Concentration Label Please refer to vial label for lot-specific concentration
      Preservative≤0.1% sodium azide
      CommentsAntibody should be titrated for optimal results in individual systems.
      Storage -20°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesLee, J., et al. 2007. Mol. Cell Prot. 4, 669.
      Le Bras, M., et al. 2006. Cancer Res. 18, 9143.
      Loiseau, D., et al. 2002. Exp. Cell Res. 1, 12.