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567816 Src Family Protein Tyrosine Kinase Inhibitor Set

567816
  
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      Overview

      Replacement Information

      Key Spec Table

      Description
      Overview

      This product has been discontinued.





      Contains 20 mg of Genistein (Cat. No. 345834), 100 µg of Herbimycin A, Streptomyces sp. (Cat. No. 375670), and 1 mg each of PP2 (Cat. No. 529573) and PP3 (Cat. No. 529574).
      Catalogue Number567816
      Brand Family Calbiochem®
      References
      Product Information
      FormSolid
      Applications
      Biological Information
      Primary TargetEGFR
      Secondary targetP60V-Src, JAK2, Hck, P56lck, PP2
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 40

      Limited evidence of a carcinogenic effect.
      S PhraseS: 22-36

      Do not breathe dust.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Multiple Toxicity Values, refer to MSDS
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Src Family Protein Tyrosine Kinase Inhibitor Set Certificates of Analysis

      TitleLot Number
      567816

      Brochure

      Title
      Protein Kinase Assay and Detection Kits Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      Descriptionv-Src tyrosine kinase was the first oncogenic gene discovered. v-Src's homologue c-Src, the normal cellular gene, was then identified as the proto-oncogene found in all cells. It was found that mutations of this gene could trigger uncontrolled cell growth or cancer. A single mutation in the tail of this protein can keep the protein in its active state at all times, and mutations in the SH3 domain have also been found to contribute to Src's oncogenic activity. With this discovery, researchers started studying the structure and function of Src to determine how the protein was regulated.

      Calbiochem® brand provides a convenient set of 4 Src Inhibitors for your research needs.
      FormSolid
      Intert gas (Yes/No) Packaged under inert gas
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Toxicity Multiple Toxicity Values, refer to MSDS