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Detergent-Mediated Viral Inactivation for Multiple Modalities

Webinar

Detergent-mediated viral inactivation is a key strategy for ensuring viral safety in biopharmaceutical manufacturing. This webinar explores its application across multiple modalities, including monoclonal antibodies, plasma products, and gene therapies. 

Learn how detergents disrupt viral envelopes to achieve effective inactivation while also enabling process efficiencies through dual functionality in cell lysis and viral clearance. Through case studies, we will compare performance with and without solvent systems and discuss the shift toward sustainable alternatives to legacy detergents.

In this Expert Connect, participants will be able to:

  • Understand the role of detergents in viral inactivation across modalities
  • Learn how dual-function detergents enable both cell lysis and viral clearance
  • Compare viral inactivation performance with and without solvent systems
  • Explore sustainable alternatives to legacy detergents like TritonTM X-100

Speakers

Janice Tan, Ph.D.

Janice Tan, Ph.D.

Merck

Head of Upstream, Process Materials and Process Consultancy Asia Pacific excluding China

Janice Tan heads the upstream, process materials and process consultancy team in Merck Asia Pacific excluding China. She and her team of scientists and engineers are responsible for providing technical consultation on upstream bioprocessing, bioprocess manufacturing optimization and troubleshooting. With over 23 years of experience in the biopharmaceutical industry, she has led multiple successful projects starting from cell line development to bioreactor scale-up by presenting holistic and innovative solutions to customers producing biotherapeutics. Janice received her Ph.D. in Biochemistry from the National University of Singapore.

Kakolie Banerjee, PhD

Kakolie Banerjee, PhD

Merck

R&D Manager (Virology), Scientific and Validation Services

Kakolie G. Banerjee is the R&D Manager (Virology) in the Virology group within Process Solutions organization at Merck. She and her team support viral inactivation and clearance studies using model mammalian viruses and bacteriophage. They support product development, generate applications data for existing products, engage in post-launch and manufacturing support, along with capability and method development. Prior to this role, she worked as a Staff Scientist at Sample6 (now Corvium/Neogen) and helped developed an AOAC-Certified high-throughput phage-based foodborne pathogen detection assay. She did her B.Sc. in Life Science from Delhi University, an M.S. in Food Safety from North Dakota State University and her Ph.D. in Food Science from Pennsylvania State University.

Rain Lee

Rain Lee

Merck

 Customer Application Consultant

Rain has over 10 years of experience in chemistry, life sciences, and bioprocessing, specializing in upstream applications from cell line development to fed-batch and continuous perfusion. She leads go-to-market strategy for upstream innovations in APeC (Asia Pacific excluding China), blending technical expertise with commercial insight. Rain supports emerging biotech, CDMOs, and large biopharma, building lasting partnerships to drive innovation and growth.