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ABN14-25UG Anti-Brain lipid binding protein (rabbit polyclonal)

Detect Brain lipid binding protein using this Anti-Brain lipid binding protein Antibody validated for use in WB, IH.

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ABN14-25UG
25 μg  
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      Description
      Catalogue NumberABN14-25UG
      DescriptionAnti-Brain lipid binding protein (rabbit polyclonal)
      Alternate Names
      • Brain lipid-binding protein
      • Fatty acid-binding protein 7
      • Mammary-derived growth inhibitor related
      • brain lipid binding protein
      • fatty acid binding protein 7, brain
      • mammary-derived growth inhibitor-related
      Background InformationBLBP (Brain lipid-binding protein) belongs to a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. BLBPs play essential roles in fatty acid uptake, transport and metabolism. BLBP can be used as a molecular marker for radial glia (a major neural progenitor cell type and a scaffolding supporting neuronal migration) in the developing central nervous system. Radial glia play an essential role in the generation of the cerebral cortex through their function as neuronal precursors and as neuronal migration guides.
      References
      Product Information
      FormatAffinity Purified
      Control
      • P1 mouse brain tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Brain lipid binding protein using this Anti-Brain lipid binding protein Antibody validated for use in WB, IH.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:300 dilution of ABN14 antibody from a previous lot detected Brain lipid binding protein in mouse cerebellum tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Brain lipid-binding protein.
      EpitopeCytoplasmic Domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityThis antibody recognizes Brain lipid-binding protein.
      Species Reactivity
      • Mouse
      • Human
      Species Reactivity NoteProven to react with mouse. Predicted to react with human based on 100% sequence homology. Rat homology - 88%.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq].
      Gene Symbol
      • FABP7
      • B-FABP
      • MRG
      • BLBP
      • FABPB
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummaryFUNCTION: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers By similarity.

      SUBCELLULAR LOCATION: Cytoplasm.

      TISSUE SPECIFICITY: Expressed in brain and other neural tissues.

      DOMAIN: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.

      SEQUENCE SIMILARITIES: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      Molecular Weight~ 15 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in P1 mouse brain tissue lysate.

      Western Blot Analysis: 0.01 µg/ml of this antibody detected Brain lipid-binding protein in 10 µg of P1 mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size25 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN14-25UG 04054839342608

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