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SCT142 BioTracker 488 Green Microtubule Cytoskeleton Dye

Live cell imaging microtubule dye for imaging the cytoskeleton of living cells

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SCT142
1 kit  
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      Overview

      Replacement Information
      Description
      Catalogue NumberSCT142
      DescriptionBioTracker 488 Green Microtubule Cytoskeleton Dye
      OverviewCytoskeleton proteins such as actin and tubulin play an important role in cell structure and motility. Dysregulation of cytoskeletal proteins are also involved in cancer metastasis and disease. Taxol binds to polymerized tubulin and stabilizes microtubules, resulting in inhibition of mitosis. However, fluorescent taxol compounds like the BioTracker Microtubule Cytoskeleton dyes are less disruptive of microtubule dynamics and cell division, presumably due to lower binding affinity of the fluorescent probe compared to taxol itself.

      The BioTracker Cytoskeleton Microtubule Dye is a green fluorescent cell-permeable taxol probe for imaging the microtubule cytoskeleton in live cells. It is a simple, rapid and sensitive stain that can be detected using the FITC channel. The dye is supplied with a vial of 100mM verapamil, an efflux pump inhibitor that may improve probe retention and staining in certain cell types.

      Spectral Properties
      Absorbance: 500nm
      Emission: 515nm
      Alternate Names
      • Live cell imaging probe
      References
      Product Information
      Components
      • 1) 1 vial of 50µL BioTracker 488 Green Microtubule Cytoskeleton Dye (1000X in DMSO) (CS224593)
      • 2) 1 vial of 100µL Verapamil HCL (100mM in DMSO) (CS224592)
      Detection methodFluorescence
      PresentationLiquid
      Applications
      ApplicationLive cell imaging microtubule dye for imaging the cytoskeleton of living cells
      Key Applications
      • Cell Based Assays
      Application NotesLive cell fluorescent imaging
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceSpectral Properties
      Absorbance: 500nm
      Emission: 515nm
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore BioTracker™ 488 Green Microtubule Cytoskeleton Dye at 2-8ºC. Protect From Light.
      Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
      Packaging Information
      Material Size1 kit
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCT142 04054839565984