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Merck

RCI1MAG-87K

MILLIPLEX® Rat Cardiac Injury Panel 1

Configurable Rat Cardiac Injury 7-Plex Panel 1

Synonym(s):

Rat myocardial injury panel, cardiovascular biomarker panel for rats, rat cardiac remodeling assay, rat cardiotoxicity detection, rat heart failure biomarkers

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000


Product Name

MILLIPLEX® Rat Cardiac Injury Panel 1,

Quality Segment

product line

Milliplex®

species reactivity

rat

packaging

pkg of 1 ea

assay range

recovery range: 80-100%
(2 Hour Protocol), recovery range: 86-103%
(Overnight Protocol), sensitivity: 7-155 pg/mL
(Overnight Protocol; MinDC+2SD), sensitivity: 9-86 pg/mL
(2 Hour Protocol; MinDC+2SD), standard curve range: 123-90,000 pg/mL
(cTnI), standard curve range: 21-15,000 pg/mL
(CKM), standard curve range: 4-3,000 pg/mL
(MYL3), standard curve range: 41-30,000 pg/mL
(FABP3), standard curve range: 41-30,000 pg/mL
(TIMP-1), standard curve range: 82-60,000 pg/mL
(FSTL1), standard curve range: 82-60,000 pg/mL
(cTnT)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Troponins (cTnI, cTnT), CKM, and MYL3 are structural proteins released during myocardial injury. FABP3 reflects early cardiac damage, while FSTL1 and TIMP-1 are involved in tissue remodeling and repair. Together, these biomarkers provide a comprehensive view of cardiac injury and recovery in rat models.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in rat serum or plasma samples.

Analytes Included: Cardiac Troponin I (cTnI), Cardiac Troponin T (cTnT), Creatine Kinase Muscle (CKM), FABP3, Follistatin-like Protein 1 (FSTL1), Myosin Light Chain 3 (MYL3), TIMP-1

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:

  • Includes 7 key biomarkers of cardiac injury and stress
  • Targets structural, enzymatic, and regulatory proteins involved in myocardial damage
  • Designed for use with rat serum or plasma samples
  • Compatible with Luminex® xMAP® technology for multiplex analysis
  • Verified for high sensitivity, specificity, and reproducibility
Benefits:

  • Enables early and accurate detection of cardiac injury in preclinical models
  • Supports research in cardiotoxicity, ischemia, heart failure, and drug safety studies
  • Reduces sample volume requirements while increasing data throughput
  • Improves efficiency in biomarker discovery and translational cardiovascular research
  • Facilitates high-throughput screening with consistent and reliable results

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3



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