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539149 Proteasome Substrate VI, Fluorogenic - CAS 90468-18-1 - Calbiochem

A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Z-ARR-AMC, 2HCl

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539149
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539149-5MGCN
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      Description
      OverviewA fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome. Also reported to be a specific substrate for cathepsin B.
      Catalogue Number539149
      Brand Family Calbiochem®
      SynonymsZ-ARR-AMC, 2HCl
      References
      ReferencesGeier, E., et al. 1999. Science 283, 978.
      Dick, T.P., et al. 1998. J. Biol. Chem. 273, 25637.
      Product Information
      CAS number90468-18-1
      ATP CompetitiveN
      FormWhite to off-white solid
      FormulationSupplied as hydrochloride salt.
      Hill FormulaC₃₃H₄₄N₁₀O₇ · 2HCl
      Chemical formulaC₃₃H₄₄N₁₀O₇ · 2HCl
      HS Code3823 70 90
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetProteasome
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Peptide SequenceZ-Ala-Arg-Arg-AMC
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      539149-5MGCN 04055977195569

      Documentation

      Proteasome Substrate VI, Fluorogenic - CAS 90468-18-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Proteasome Substrate VI, Fluorogenic - CAS 90468-18-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      539149

      References

      Reference overview
      Geier, E., et al. 1999. Science 283, 978.
      Dick, T.P., et al. 1998. J. Biol. Chem. 273, 25637.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-November-2018 JSW
      SynonymsZ-ARR-AMC, 2HCl
      DescriptionA fluorogenic substrate for assaying trypsin-like activity of proteasome. Also serves as a substrate for cathepsin B. Excitation max: 360-380 nm; emission max.: 430-460 nm.
      FormWhite to off-white solid
      FormulationSupplied as hydrochloride salt.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number90468-18-1
      Chemical formulaC₃₃H₄₄N₁₀O₇ · 2HCl
      Peptide SequenceZ-Ala-Arg-Arg-AMC
      Purity≥98% by HPLC
      SolubilityDMSO (200 mg/ml), methanol, or 80% acetic acid (50 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C
      Toxicity Standard Handling
      ReferencesGeier, E., et al. 1999. Science 283, 978.
      Dick, T.P., et al. 1998. J. Biol. Chem. 273, 25637.