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About This Item
Empirical Formula (Hill Notation):
C34H60D7NO3
CAS Number:
Molecular Weight:
544.94
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.12
Assay:
>99% (TLC)
Form:
powder
Product Name
C16 Ceramide-d7 (d18:1-d7/16:0), Avanti Research™ - A Croda Brand 860676P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860676P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860676P
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]
InChI
1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)/b29-27+/t32-,33+/m0/s1/i1D3,3D2,5D2
InChI key
YDNKGFDKKRUKPY-HJSOYJPBSA-N
General description
C16 Ceramide (d18:1/16:0) is a synthetic ceramide containing sphingosine with palmitic acid. It is synthesized from ceramide synthase 6 (CerS6). C16 Ceramide-d7 (d18:1-d7/16:0) is a deuterated derivative of ceramide d18:1/16:0.
Application
C16 Ceramide-d7 (d18:1-d7/16:0), has been used as a standard to measure the amount of C16 ceramide in skeletal muscle by liquid chromatography–mass spectrometry (LC-MS).
Biochem/physiol Actions
C16 Ceramide plays a vital role in apoptotic signaling. Examining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma facilitates the prognosis of fatal outcome of coronary artery disease. A newly described and validated liquid chromatography-tandem mass spectrometry methodology uses C16 Ceramide (d18:1/16:0) in a stable isotope form for their clinical-scaled measurement.
Packaging
5 mL Amber Glass Screw Cap Vial (860676P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
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