5.05415
Cyclothiazide
Synonym(s):
Cyclothiazide
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About This Item
Empirical Formula (Hill Notation):
C14H16ClN3O4S2
CAS Number:
Molecular Weight:
389.88
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (sum of two diastereoisomers, HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
assay
≥98% (sum of two diastereoisomers, HPLC)
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 100 mM, ethanol: 25 mM
storage temp.
2-8°C
InChI
1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)
InChI key
BOCUKUHCLICSIY-UHFFFAOYSA-N
General description
Selectively blocks AMPA receptor desensitization and potentiates AMPA and kainate-induced increases in intracellular calcium and norepinephrine release.
Biochem/physiol Actions
Primary Target
AMPA receptor
AMPA receptor
Other Notes
David, J., et al. 1996. J. Neurosci.16, 200.
Lijequist, S., et al. 1995. Biochem. Pharmacol.50, 1761.
Lijequist, S., et al. 1995. Biochem. Pharmacol.50, 1761.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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