PFAS Tested Additives and Solvents

LiChrosolv^® PFAS-tested solvents

LiChrosolv^® PFAS-tested solvents, including water, acetonitrile, and methanol, are ultra-high-purity solvents designed for UHPLC-MS and liquid chromatography-mass spectrometry (LC-MS) applications.

The high sensitivity of LC-MS instruments enables the detection of PFAS at trace levels. As a result, the solvents used in PFAS analysis must be free from PFAS contamination. Even low levels of PFAS in analytical solvents can lead to false-positive results or overestimation of PFAS concentrations in samples, compromising the accuracy and reliability of analytical data and conclusions. Ensuring solvent purity is therefore essential for dependable PFAS analysis.

LiChrosolv^® PFAS-tested solvents are specifically developed to meet the stringent requirements of PFAS testing. Each batch undergoes rigorous quality control and is tested against all analytes specified in EPA methods EPA 533, EPA 537.1, and EPA 1633. These solvents are formulated to minimize background interference and contain no PFAS compounds above the reporting limits defined by the respective EPA method. This supports accurate identification and quantitation of PFAS analytes while reducing the risk of false-positive or false-negative results in LC-MS/MS analysis.

LiChropur™ PFAS-tested additives

LiChropur™ PFAS-tested additives include acetic acid, formic acid, ammonia and ammonium acetate. These high-purity additives are used as mobile-phase modifiers and eluent additives in LC-MS/MS methods for PFAS analysis. They are tested for all EPA 1633 compounds to ensure minimal PFAS background contamination, helping to maintain analytical accuracy and confidence in PFAS testing results. Furthermore, the elemental impurities are low to avoid possible adduct formation during LC-MS analysis.

PFAS testing features and benefits:

• Application security: Tested for all PFAS listed in EPA methods 533, 537.1 and 1633.
• Faster compliance, lower cost: Meets EPA 1633 expectations, eliminating the need for in-house batch validation.
• Ultra-low background interference: Lowest impurity profiles support clean baselines and confident quantitation.
• LC-MS ready: Optimized for ESI and APCI ionization in both positive and negative modes.
• Reduced contamination risk: Packed in high-quality borosilicate glass bottles for minimized metal ion contamination
• Controlled trace metals: Low-ppb metal levels minimize ion suppression and metal adduct formation.
• Assured particulate purity: Microfiltered to 0.2 μm for consistent performance in sensitive workflows.