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DR1084 Anti-GCLM Rabbit pAb

DR1084
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      Rb
      Description
      Overview

      This product has been discontinued.





      Recognizes the GCLM protein.
      Catalogue NumberDR1084
      Brand Family Calbiochem®
      SynonymsAnti-Glutamate-Cysteine Ligase Modifier Subunit
      Application Data
      Detection of human GCLM by immunoprecipitation followed by immunoblotting. Sample: Whole cell lysate from cells transfected wtih GCLM. Antibody for IP: Anti-GCLM Rabbit pAb (Cat. No. DR1084) (ratio of antibody: protein A beads is 1:50 to 1:100). Antibody for IB: Anti-GCLM Rabbit pAb. Detection: chemiluminescence.
      References
      Product Information
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      Applications
      Key Applications Immunoprecipitation
      Application NotesImmunoprecipitation (see comments)
      Biological Information
      ImmunogenFull-length, human GCLM (aa 1-274)
      ImmunogenHuman
      HostRabbit
      IsotypeIgG
      SourceVariables associated with assay conditions will dictate the proper working dilution.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Regulatory Review
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-November-2010 RFH
      SynonymsAnti-Glutamate-Cysteine Ligase Modifier Subunit
      ApplicationImmunoprecipitation (see comments)
      Application Data
      Detection of human GCLM by immunoprecipitation followed by immunoblotting. Sample: Whole cell lysate from cells transfected wtih GCLM. Antibody for IP: Anti-GCLM Rabbit pAb (Cat. No. DR1084) (ratio of antibody: protein A beads is 1:50 to 1:100). Antibody for IB: Anti-GCLM Rabbit pAb. Detection: chemiluminescence.
      DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the GCLM protein.
      BackgroundGlutamate-cysteine ligase, also known as γ-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
      HostRabbit
      Immunogen speciesHuman
      ImmunogenFull-length, human GCLM (aa 1-274)
      IsotypeIgG
      Specieshuman
      FormLiquid
      FormulationUndiluted serum.
      SourceVariables associated with assay conditions will dictate the proper working dilution.
      PreservativeNone
      Storage -20°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Regulatory Review