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539563 PKCδ Peptide Substrate

539563
  
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      Overview

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      Description
      Overview

      This product has been discontinued.





      A highly specific substrate for the protein kinase Cδ isozyme (PKCδ; Km = 22.9 µM). The sequence corresponds to amino acid residues 422 - 443 of murine εEF-1α containing Thr431, which is phosphorylated by PKCδ. Arg429 is essential for recognition of this peptide as PKCδ substrate.
      Catalogue Number539563
      Brand Family Calbiochem®
      SynonymsRFAVRDMRQTVAVGVIKAVDKK, Protein Kinase Cδ Peptide Substrate
      References
      ReferencesKielbassa, K., et al. 1995. J. Biol. Chem. 270, 6156.
      Product Information
      ATP CompetitiveN
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₀₉H₁₉₁N₃₅O₂₉S
      Chemical formulaC₁₀₉H₁₉₁N₃₅O₂₉S
      Hygroscopic Hygroscopic
      ReversibleN
      Applications
      Biological Information
      Primary TargetA highly specific substrate for the protein kinase Cδ isozyme
      Primary Target IC<sub>50</sub>Km = 22.9 µM for protein kinase Cδ isozyme (PKCδ)
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-Arg-Phe-Ala-Val-Arg-Asp-Met-Arg-Gln-Thr-Val-Ala-Val-Gly-Val-Ile-Lys-Ala-Val-Asp-Lys-Lys-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      PKCδ Peptide Substrate MSDS

      Title

      Safety Data Sheet (SDS) 

      PKCδ Peptide Substrate Certificates of Analysis

      TitleLot Number
      539563

      References

      Reference overview
      Kielbassa, K., et al. 1995. J. Biol. Chem. 270, 6156.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-September-2008 RFH
      SynonymsRFAVRDMRQTVAVGVIKAVDKK, Protein Kinase Cδ Peptide Substrate
      DescriptionA highly specific substrate for the protein kinase Cδ isozyme (PKCδ; Km = 22.9 µM). The sequence corresponds to residues 422-443 of murine eEF-1α, containing Thr431, which is phosphorylated by PKCδ.
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₁₀₉H₁₉₁N₃₅O₂₉S
      Peptide SequenceH-Arg-Phe-Ala-Val-Arg-Asp-Met-Arg-Gln-Thr-Val-Ala-Val-Gly-Val-Ile-Lys-Ala-Val-Asp-Lys-Lys-OH
      Purity≥95% by HPLC
      SolubilityDMSO or H₂O (25 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesKielbassa, K., et al. 1995. J. Biol. Chem. 270, 6156.