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512745 Patulin, Penicillium expansum

512745
  
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₇H₆O₄ 149-29-1
      Description
      Overview

      This product has been discontinued.

      We apologize for the inconvenience, but we do not currently have an alternative product.





      A fungal mycotoxin with antibacterial and cytostatic properties. Inhibits cell-free microtubule polymerization in a concentration-dependent manner. Binds covalently to reactive thiol groups of microtubule proteins. A protein prenylation inhibitor that also reduces store-mediated Ca2+ entry into cells and inhibits potassium uptake.
      Catalogue Number512745
      Brand Family Calbiochem®
      References
      ReferencesRosada, T.A., and Sage, S.O. 2000. Biochem. J. 347, 183. Pfeiffer, E., et al. 1998. Carcinogenesis 19, 1313. Kahn, J. 1957. J. Pharmacol. Exp. Ther. 121, 234.
      Product Information
      CAS number149-29-1
      FormWhite crystalline solid
      Hill FormulaC₇H₆O₄
      Chemical formulaC₇H₆O₄
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSLV2625000
      Safety Information
      R PhraseR: 26/27/28-40

      Very toxic by inhalation, in contact with skin and if swallowed.
      Limited evidence of a carcinogenic effect.
      S PhraseS: 22-36/37/39-45

      Do not breathe dust.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage FREEZER (-20°C)
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Patulin, Penicillium expansum Certificates of Analysis

      TitleLot Number
      512745

      References

      Reference overview
      Rosada, T.A., and Sage, S.O. 2000. Biochem. J. 347, 183. Pfeiffer, E., et al. 1998. Carcinogenesis 19, 1313. Kahn, J. 1957. J. Pharmacol. Exp. Ther. 121, 234.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-December-2008 RFH
      DescriptionA fungal mycotoxin with antibacterial and cytostatic properties. Inhibits cell-free microtubule polymerization in a concentration-dependent manner. Binds covalently to reactive thiol groups of microtubule proteins. A protein prenylation inhibitor that also reduces store-mediated Ca2+ entry into cells and inhibits potassium uptake.
      FormWhite crystalline solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number149-29-1
      RTECSLV2625000
      Chemical formulaC₇H₆O₄
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO or ethyl acetate
      Storage FREEZER (-20°C)
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
      Toxicity Highly Toxic & Carcinogenic / Teratogenic
      Merck USA index14 7053
      ReferencesRosada, T.A., and Sage, S.O. 2000. Biochem. J. 347, 183. Pfeiffer, E., et al. 1998. Carcinogenesis 19, 1313. Kahn, J. 1957. J. Pharmacol. Exp. Ther. 121, 234.