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662094 Ubiquitin Conjugating Enzyme 6, His•Tag®, Human, Recombinant, E. coli

662094
  
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      Overview

      Replacement Information

      Key Spec Table

      Description
      Overview

      This product has been discontinued.





      Recombinant, human ubiquitin conjugating enzyme 6 fused to a His•Tag® sequence and expressed in E. coli. E2s are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-lysine of proteins designated for degradation. A closely related member of the UbcH5 family, UbcH6 has been implicated in ER degradation of aberrant proteins. UbcH6 utilizes Nedd4 as its ubiquitin-protein ligase.
      Catalogue Number662094
      Brand Family Calbiochem®
      Synonyms(His)₆ UbcH6 (E2)
      References
      ReferencesAnan, T., et al. 1998. Genes Cells 3, 751.
      Varshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
      Seufert, W., et al. 1990. EMBO J. 9, 4535.
      Product Information
      FormLiquid
      FormulationIn 200 mM NaCl, 50 mM Hepes, 0.1 mM DTT, 10% glycerol, pH 8.0.
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Ubiquitin Conjugating Enzyme 6, His•Tag®, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      662094

      References

      Reference overview
      Anan, T., et al. 1998. Genes Cells 3, 751.
      Varshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
      Seufert, W., et al. 1990. EMBO J. 9, 4535.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-September-2008 RFH
      Synonyms(His)₆ UbcH6 (E2)
      DescriptionRecombinant, human ubiquitin conjugating enzyme 6 fused to a His•Tag® sequence and expressed in E. coli. E2 ubiquitin-conjugating enzymes are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-Lysine of proteins designated for degradation. A closely related member of the UbcH5 family, UbcH6 has been implicated in ER degradation of aberrant proteins. UbcH6 utilizes Nedd4 as its ubiquitin-protein ligase.
      FormLiquid
      FormulationIn 200 mM NaCl, 50 mM Hepes, 0.1 mM DTT, 10% glycerol, pH 8.0.
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥95% by SDS-PAGE
      Storage ≤ -70°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesAnan, T., et al. 1998. Genes Cells 3, 751.
      Varshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
      Seufert, W., et al. 1990. EMBO J. 9, 4535.