218840 InSolution™ Caspase-8 Inhibitor II - Calbiochem

218840
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₃₀H₄₃FN₄O₁₁

Pricing & Availability

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218840-250UG
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      Glass bottle 250 μg
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      Description
      Catalogue Number218840
      Brand Family Calbiochem®
      SynonymsGranzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK
      References
      ReferencesMartin, D.A., et al. 1998. J. Biol. Chem. 273, 4345.
      Sweeney, E.A., et al. 1998. FEBS Lett. 425, 61.
      Product Information
      ATP CompetitiveN
      FormLiquid
      FormulationA 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.
      Hill FormulaC₃₀H₄₃FN₄O₁₁
      Chemical formulaC₃₀H₄₃FN₄O₁₁
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcaspase-8
      Puritysingle spot by TLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceZ-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      S PhraseS: 26

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InSolution™ Caspase-8 Inhibitor II - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      InSolution™ Caspase-8 Inhibitor II - Calbiochem Certificates of Analysis

      TitleLot Number
      218840

      References

      Reference overview
      Martin, D.A., et al. 1998. J. Biol. Chem. 273, 4345.
      Sweeney, E.A., et al. 1998. FEBS Lett. 425, 61.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-June-2008 RFH
      SynonymsGranzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK
      DescriptionA 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B.
      FormLiquid
      FormulationA 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₃₀H₄₃FN₄O₁₁
      Peptide SequenceZ-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*
      Puritysingle spot by TLC
      Storage -20°C
      Hygroscopic
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Irritant
      ReferencesMartin, D.A., et al. 1998. J. Biol. Chem. 273, 4345.
      Sweeney, E.A., et al. 1998. FEBS Lett. 425, 61.