8.00608
Propionic anhydride
for synthesis
Synonym(s):
Propionic anhydride
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About This Item
vapor pressure
1 hPa ( 20 °C)
Quality Level
assay
≥98.0% (GC)
form
liquid
autoignition temp.
285 °C
potency
2360 mg/kg LD50, oral (Rat), 10000 mg/kg LD50, skin (Rabbit)
expl. lim.
1.3-9.5 % (v/v)
pH
2.5 (20 °C, 100 g/L in H2O, calculated on the free acid)
bp
167 °C/1013 hPa
mp
-45 °C
transition temp
flash point 63 °C
density
1.01 g/cm3 at 20 °C
storage temp.
2-30°C
SMILES string
O(C(=O)CC)C(=O)CC
InChI
1S/C6H10O3/c1-3-5(7)9-6(8)4-2/h3-4H2,1-2H3
InChI key
WYVAMUWZEOHJOQ-UHFFFAOYSA-N
Application
<li><strong>Trace Amines Quantification:</strong> Propionic anhydride is used to derivatize the amino and hydroxyl groups for catecholamines and indolesin (de Bruyn et al., 2024).</li>
<li><strong>Asphaltene Oxidation Research:</strong> It is used in the oxidation of asphaltene and in the synthesis of peroxypropionic acid (Zhao et al., 2023).</li>
<li><strong>In Acylation Reactions:</strong> Used in the acylation of 1,2-methylenedioxybenzene (MDB) during the synthesis of 3,4-methylenedioxypropiophenone (MDP1P) and propionic acid.<br /> (Schiaroli et al., 2023).</li>
</ul>
Analysis Note
Density (d 20 °C/ 4 °C): 1.009 - 1.011
Identity (IR): passes test
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 1
flash_point_f
145.4 °F
flash_point_c
63 °C
Certificates of Analysis (COA)
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