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MABF425 Anti-CD44 Antibody (human/mouse), PE-Cy5, clone IM7

This rat monoclonal CD44 antibody, Anti-CD44 (human/mouse), PE-Cy5, clone IM7, is validated for use in Western Blottting, IP, IHC & Flow Cytometry for the detection of CD44. This CD44 Antibody has been tested in Human and Mouse.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Gene Symbol: Cd44, Ly-24 UniProt Number: P15379
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MABF425
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MFC, IHC, IP, WBRPE-Cy5Monoclonal Antibody
Description
Catalogue NumberMABF425
DescriptionAnti-CD44 Antibody (human/mouse), PE-Cy5, clone IM7
Alternate Names
  • CD44 antigen
  • Extracellular matrix receptor III
  • ECMR-III
  • GP90 lymphocyte homing/adhesion receptor
  • HUTCH-I
  • Hermes antigen
  • Hyaluronate receptor
  • Lymphocyte antigen 24
  • Ly-24
  • Phagocytic glycoprotein 1
  • PGP-1
  • Phagocytic glycoprotein I
  • PGP-I
  • CD44
Background InformationThe IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, throµgh which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.
References
Product Information
FormatPE-Cy5
PresentationPurified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis rat monoclonal CD44 antibody, Anti-CD44 (human/mouse), PE-Cy5, clone IM7, is validated for use in Western Blottting, IP, IHC & Flow Cytometry for the detection of CD44. This CD44 Antibody has been tested in Human and Mouse.
Key Applications
  • Flow Cytometry
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blotting
Biological Information
ImmunogenImmunogen information for this antibody is proprietary information.
CloneIM7
Concentration0.2 mg/mL
HostRat
IsotypeIgG2bκ
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Gene Symbol
  • Cd44
  • Ly-24
Purification MethodSize Exclusion Chromatography
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceThe monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.125 µg of this antibody detected CD44 in one million C57Bl/6 splenocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsIt is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABF425 04053252960161