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AB9415 Anti-Cannabinoid Receptor 1 Antibody

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AB9415
50 µg  
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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, Mk, RICC, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9415
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Cannabinoid Receptor 1 Antibody
Alternate Names
  • CB1
References
Product Information
FormatAffinity Purified
HS Code3002 15 90
PresentationAffinity purified immunoglobulin. Liquid in PBS, with less than 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Cannabinoid Receptor 1 Antibody detects level of Cannabinoid Receptor 1 & has been published & validated for use in IC, IH(P).
Key Applications
  • Immunocytochemistry
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry on formalin fixed paraffin embedded tissue sections.

Immunocytochemistry on acetone fixed cells.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenSynthetic peptide from the 3rd cytoplasmic domain of human Cannabinoid Receptor 1. The immunogen sequence has 100% homology with mouse.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes Cannabinoid Receptor 1 [CB1].
Species Reactivity
  • Human
  • Monkey
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a protein that is one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the family of guanine-nucleotide-binding protein (G-protein) coupled receptors which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Two transcript variants encoding different isoforms have been described for this gene.
Gene Symbol
  • CNR1
  • CNR
  • CB1K5
  • CANN6
  • CB1A
  • CB-R
  • CB1
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P21554 # Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Isoform 2 and isoform 3 have altered ligand binding.
SIZE: 472 amino acids; 52858 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Widely expressed.
SIMILARITY: SwissProt: P21554 ## Belongs to the G-protein coupled receptor 1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Availability by Geography
  • This product is not available for sale in Japan.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB9415 04053252280214

Documentation

Anti-Cannabinoid Receptor 1 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Cannabinoid Receptor 1 Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI- CANNABINOID RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2152957 2152957
RABBIT ANTI- CANNABINOID RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2410978 2410978
RABBIT ANTI- CANNABINOID RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2143906 2143906
RABBIT ANTI- CANNABINOID RECEPTOR 1 - 3255327 3255327
RABBIT ANTI- CANNABINOID RECEPTOR 1 - 4187070 4187070
RABBIT ANTI- CANNABINOID RECEPTOR 1 -2638910 2638910
RABBIT ANTI- CANNABINOID RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2925266

Data Sheet

Title
RABBIT ANTI- CANNABINOID RECEPTOR 1