Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

233493 Coagulation Factor α-XIIa, Human Plasma

Coagulation Factor α-XIIa, Human Plasma, is a native coagulation factor α-XIIa prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation.

Coagulation Factor α-XIIa, Human Plasma MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
View Products on Sigmaaldrich.com
233493
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
233493-500UGCN Plastic ampoule 500 μg
Description
OverviewNative coagulation factor α-XIIa from human plasma prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation. α-XIIa is a serine protease responsible for activation of Factor XI to Factor XIa. Factor XIIa and prekallikrein are thought to be involved in a reciprocal activation mechanism whereby Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to Factor XIIa.
Catalogue Number233493
Brand Family Calbiochem®
References
Product Information
FormLiquid
FormulationIn 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
Quality LevelMQ100
Applications
Biological Information
Purityhomogeneous by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity50 units/mg protein (clotting assay). Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
233493-500UGCN 04055977217865

Documentation

Coagulation Factor α-XIIa, Human Plasma SDS

Title

Safety Data Sheet (SDS) 

Coagulation Factor α-XIIa, Human Plasma Certificates of Analysis

TitleLot Number
233493
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-June-2008 RFH
DescriptionNative coagulation factor α-XIIa from human plasma prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation. α-XIIa is a serine protease responsible for activation of Factor XI to Factor XIa. Factor XIIa and prekallikrein are thought to be involved in a reciprocal activation mechanism whereby Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to Factor XIIa.
FormLiquid
FormulationIn 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
Concentration Label Please refer to vial label for lot-specific concentration
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purityhomogeneous by SDS-PAGE
Specific activity50 units/mg protein (clotting assay). Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling