Agonist
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530409 Sigma-AldrichTLR8 Agonist, cpd14b - CAS 1607440-08-3 - Calbiochem (TLR8 Agonist, cpd14b - CAS 1607440-08-3 - Calbiochem)
A potent agonist of Toll-like receptor 8 agonist (TLR8, EC₅₀ = 200 nM).
530533 Sigma-AldrichTRPV4 Agonist, GSK1016790A - CAS 942206-85-1 - Calbiochem (TRPV4 Agonist, GSK1016790A - CAS 942206-85-1 - Calbiochem)
A cell-permeable, potent, selective agonist of TRPV4 channel. Enhances Ca2+ flux in a variety of human and mouse cells (EC₅₀ = 2.1 nM for human TRPV4).
681664 Sigma-AldrichWnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem (Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem)
The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
508578 Sigma-AldrichTSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem (TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem)
A 4'-chloro derivative of diazepam that lacks affinity for GABA-A receptors, but can serve as a ligand for the peripheral benzodiazepine receptor.
681665 Sigma-AldrichWnt Agonist - CAS 853220-52-7 - Calbiochem (Wnt Agonist - CAS 853220-52-7 - Calbiochem)
Wnt Agonist, CAS 853220-52-7, is a cell-permeable, potent, and selective activator of Wnt signaling. Does not inhibit the activity of GSK-3β (IC50 greater than 60 µM).
681667 Sigma-AldrichWnt Agonist II, SKL2001 - CAS 909089-13-0 - Calbiochem (Wnt Agonist II, SKL2001 - CAS 909089-13-0 - Calbiochem)
Wnt Agonist II, SKL2001, CAS 909089-13-0, upregulates β-catenin-regulated transcription by disrupting β-catenin & Axin interaction. Prevents β-catenin phosphorylation and proteasomal degradation.
126920 Sigma-AldrichALDH2 Agonist, Alda-1 - CAS 349438-38-6 - Calbiochem (ALDH2 Agonist, Alda-1 - CAS 349438-38-6 - Calbiochem)
ALDH2 Agonist, Alda-1, CAS 349438-38-6, is a cell-permeable, selective enhancer the activity of both the wild-type ALDH2*1 and the East Asian E487K mutant ALDH2*2 forms of mitochondrial ALDH2.
371706 Sigma-AldrichGPR40 Agonist - CAS 885101-89-3 - Calbiochem (GPR40 Agonist - CAS 885101-89-3 - Calbiochem)
The GPR40 Agonist, also referenced under CAS 885101-89-3, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Cell Signaling applications.
532583 Sigma-AldrichTLR1/TLR2 Agonist II, CU-T12-9 - CAS 1821387-73-8 - Calbiochem (TLR1/TLR2 Agonist II, CU-T12-9 - CAS 1821387-73-8 - Calbiochem)
TLR1/TLR2 Agonist & CU-T12-9
539109 Sigma-AldrichPAR-2 Agonist I - Calbiochem (PAR-2 Agonist I - Calbiochem)
The PAR-2 Agonist I controls the biological activity of PAR-2. This small molecule/inhibitor is primarily used for Activators/Inducers applications.