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Small GTPase Activation Assays | Life Science Research | Merck
Cytoskeletal signaling complexes include G-protein complexes, focal adhesions, and adherens junctions. Focal adhesions and adherens junctions link the cell exterior to the plasma membrane and the actin cytoskeleton, acting as key initiators of signaling pathways in response to cell adhesion. -
Oxidative Stress Antibodies | Life Science Research | Merck
Protein oxidation is frequently associated with excess oxidative stress in the cell. Our protein oxidation detection kits in WB (OxyBLOT™), Elisa (OxyELISA™), ICC (OxyICC), and IHC (OxyIHC) formats detect carbonyl groups introduced on proteins. -
Cell Signaling Assay Kits Using Luminex® Technology | Life Science Research | Merck
Measure activation of cell signaling pathways, using MILLIPLEX® bead-based multiplex assays. -
Cell Signaling Multiplex Assays Using Luminex® Technology | Life Science Research | Merck
Cell signaling multiplex assays enable accurate relative quantitation of total and phosphorylated forms of signaling proteins, revealing connections within your networks of interest. -
Cell Signaling Antibodies & Assays | Life Science Research | Merck
Cell signaling pathways transmit the reactions of cells to various internal and external stimuli. Intracellular signal transduction is often accomplished through a series of reversible protein phosphorylation events. -
Protein Phosphorylation | Life Science Research | Merck
Protein phosphorylation systems are composed of at least three components: (a) phosphoproteins (b) kinases and (c) phosphatases, that dephosphorylate the phosphoproteins, thereby restoring the system to its basal stage. -
Antibodies to Acetylated and Deacetylated Proteins | Life Science Research | Merck
We offer a selection of assay kits and antibodies to measure acetylation and deacetylation activity, helping to elucidate the relationship between chromatin modification pathways and gene regulation. -
Ubiquitin Antibodies | Life Science Research | Merck
Our tools for studying ubiquitination will help you understand the biological role and importance of the ubiquitin-proteasome pathway that has been implicated in several forms of malignancy and in the pathogenesis of several genetic diseases. -
Antibodies for Cytoplasmic Signaling | Life Science Research | Merck
Cytoplasmic signaling proteins play crucial roles in cell cycle, targeted proteolysis, protein trafficking, cytoskeletal organization, and gene expression.