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34857

1,4-Dioxane

suitable for HPLC, ≥99.5%

Synonym(s):

Diethylene oxide, Dioxane

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About This Item

Linear Formula:
C4H8O2
CAS Number:
123-91-1
Molecular Weight:
88.11
UNSPSC Code:
41116105
NACRES:
NA.21
PubChem Substance ID:
329755066
EC Number:
204-661-8
Beilstein/REAXYS Number:
102551
MDL number:
MFCD00006571
Assay:
≥99.5%
Grade:
HPLC grade
Technique(s):
HPLC: suitable
Bp:
100-102 °C (lit.)
Vapor pressure:
27 mmHg ( 20 °C), 40 mmHg ( 25 °C)
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grade

HPLC grade

vapor density

3 (vs air)

vapor pressure

27 mmHg ( 20 °C), 40 mmHg ( 25 °C)

assay

≥99.5%

form

liquid

autoignition temp.

356 °F

expl. lim.

22 %

technique(s)

HPLC: suitable

impurities

≤0.001% non-volatile matter, ≤0.002% free acid (as CH3COOH), ≤0.01% peroxides (as H2O2), ≤0.05% water (Karl Fischer)

transmittance

220 nm, ≥20%, 270 nm, ≥80%, 300 nm, ≥98%

refractive index

n20/D 1.422 (lit.)

pH

6.0-8 (20 °C, 500 g/L)

bp

100-102 °C (lit.)

mp

10-12 °C (lit.)

density

1.034 g/mL at 25 °C (lit.)

UV absorption

λ: 220 nm Amax: ≤0.70, λ: 235 nm Amax: ≤0.50, λ: 250 nm Amax: ≤0.20, λ: 270 nm Amax: ≤0.10, λ: 295-400 nm Amax: ≤0.01

SMILES string

C1COCCO1

application(s)

food and beverages

InChI

1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

InChI key

RYHBNJHYFVUHQT-UHFFFAOYSA-N

General description

1,4-Dioxane is widely used as a solvent for various organic compounds in industry. It is a non-biodegradable contaminant found in industrial effluents. Its oxidative degradation by using oxygen and ozone has been useful in converting it into biodegradable products, which can be easily removed by conventional methods.

Application

1,4-Dioxane may be employed as a solvent in the synthesis of N-(4-(prop-2-ynyloxy)phenyl)acetamide and 3-(4-(prop-2-ynyloxy)phenyl)-3,4-dihydro-2H-benzo[e][1,3]oxazine.
High-purity, multipurpose solvent, tested for suitability in:
  • HPLC
  • Spectrophotometry
  • Residual testing
  • LC-MS applications.

Reported as a solvent in:
  • HPLC-MS study of fat-soluble vitamins (FSVs)
  • GC-MS analysis of phthalates in workplace air

Suitable for HPLC, spectrophotometry, environmental testing

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

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signalword

Danger

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

EUH019,EUH066

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Class I Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

34857-2.5L:4.548173259604E12 + 34857-1L:4.548173259598E12 + 34857-500ML:4.54817334117E12 + 34857-100ML:4.548173219493E12 + 34857-2L:4.548173219509E12

jan

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