Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
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Select A Species, Panel Type, Kit or Sample Type
To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
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96-Well Plate
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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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Mitochondria responsible for generating ATP, but they act as sensors of cellular distress, and are the first parts of the cell to send and respond to cell death signals. Explore how mitochondrial dysfunction affects the aging process in Hallmarks of aging.
Monitoring the impact on mitochondria and related cell health markers applications is an important part of drug screening programs, pathway mapping, apoptosis, and disease research.
Mitochondrial detection antibodies and assays are used to help detect and study mitochondrial proteins and membrane potential changes in Apoptotic cells.
Organisms depend on multiple nutrient sensing pathways to make sure that the cells and tissue obtain just the right amount of necessary nutrients. Metabolic activities can put stress on our cells. Too much activity, and changes in nutrient availability and composition cause cells to age faster.
The Hallmarks of Aging are rigorously researched phenomena that directly influence aging. Aging is the primary risk factor for major human pathologies, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. The 9 hallmarks include Genomic instability, Telomere attrition, Epigenetic alterations, Loss of proteostasis, Deregulated nutrient sensing, Mitochondrial dysfunction, Cellular senescence, Stem cell exhaustion, Altered intercellular communication.
Apoptosis is the ability of tumor cells to elude programmed cell death. Antibodies and Assays are used in many steps of the apoptosis pathway such as: The detection process.
Parameters of cell health include apoptosis, oxidative stress, mitochondrial health, DNA integrity, and cell cycle profile. FlowCellect Kits enables an easier and accurate studies of cell cycle and cell populations.
Muse kits were designed to help researchers not only detect and quantify apoptosis, but to also characterize it by examining phosphatidylserine translocation, mitochondrial membrane potential (??m), and caspase activation.
Muse kits were designed to help researchers not only detect and quantify apoptosis, but to also characterize it by examining phosphatidylserine translocation, mitochondrial membrane potential (??m), and caspase activation.
As we age, our stem cells eventually lose their ability to divide and we are unable to replace the stem cells that have migrated, differentiated, or died. As a result, we show outward symbols of aging.