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Merck

MAB1987

Anti-Integrin beta 1 (CD29) Antibody

CHEMICON®, mouse monoclonal, P4C10

Sinónimos:

CD29

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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
P4C10, monoclonal
Species reactivity:
human
Application:
ELISA, ICC, IP, WB
Citations:
74
Servicio técnico
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Nombre del producto

Anti-Integrin β1 Antibody, clone P4C10, culture supernatant, clone P4C10, Chemicon®

biological source

mouse

Quality Level

antibody form

culture supernatant

antibody product type

primary antibodies

clone

P4C10, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG2a

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... ITGB1(3688)

Application

Detect Integrin β1 using this Anti-Integrin β1 Antibody, clone P4C10 validated for use in ELISA, IP, WB & IC.
Inhibits attachment of UCLA-P3 cells to collagen type I (Wayner, 1991). Inhibits endodermal and keratinocytes to collagen, fibronectin and laminin. It also inhibits cell to cell adhesion. Typical dilution ranges are 1:50-1:500.

Immunoflourescence

Immunoblotting

Immunoprecipitation

ELISA

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected Integrin β1 in HeLa cells.

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Biochem/physiol Actions

Reacts with the beta-1 subunit of the integrin protein family. Appears to be human specific. Unlike many beta-1 monoclonals 4C10′s epitope is not trypsin sensitive.

Physical form

Tissue Culture supernatant, containing 0.1% sodium azide.

Preparation Note

Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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M Fornaro et al.
Molecular biology of the cell, 11(7), 2235-2249 (2000-07-11)
The integrin cytoplasmic domain modulates cell proliferation, adhesion, migration, and intracellular signaling. The beta(1) integrin subunits, beta(1C) and beta(1A), that contain variant cytoplasmic domains differentially affect cell proliferation; beta(1C) inhibits proliferation, whereas beta(1A) promotes it. We investigated the ability of
W-C Liao et al.
Placenta, 36(4), 357-364 (2015-02-11)
Glycosylation controls diverse protein functions and regulates various cellular phenotypes. Trophoblast invasion is essential for normal placental development. However, the role of glycosylation in human placenta throughout pregnancy is still unclear. The β-1,4-galactosyltransferase III (B4GALT3) has been found to regulate
Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site.
Trivedi, V; Boire, A; Tchernychev, B; Kaneider, NC; Leger, AJ; O'Callaghan, K; Covic et al.
Cell null



Número de artículo de comercio global

SKUGTIN
MAB198704053252577413