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Merck

C3821

Citrate-dextrose solution (ACD)

sterile-filtered

Sinónimos:

Acid citrate-dextrose, Anticoagulant citrate-dextrose

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Número CAS:
UNSPSC Code:
12161700
NACRES:
NA.25
MDL number:
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Nombre del producto

Citrate-dextrose solution (ACD), sterile-filtered

sterility

sterile-filtered

form

liquid

pH

4.5-5.5

storage temp.

2-8°C

Quality Level

Categorías relacionadas

Application

Citrate-dextrose solution (ACD) has been used for dilution of blood for haematological studies. It has also been used as an anticoagulant during blood collection by cardiac puncture from mice and human bone marrow isolation.
For research use only. Not for use in diagnostic procedures.

Biochem/physiol Actions

Useful for anticoagulation of whole blood; erythrocyte survival

General description

Citrate-dextrose solution (ACD) is an anticoagulant and preservative used routinely for blood storage. The ideal red blood cells shelf life is 21 days when stored in ACD solution. Red blood cells in ACD solution utilize glucose and their viability is impairs when reinfused.

Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Certificados de análisis (COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. Is Product C3821, Citrate-dextrose solution, also known as "ACD"?

    Yes. A synonym for this product is ACD, which stands for anticoagulant citrate dextrose.

  4. At what concentration should Product C3821, Citrate-dextrose solution, be used?

    Use 1 part citrate dextrose solution to 9 parts blood.

  5. What is the composition of Product C3821, Citrate-dextrose solution?

    The composition if this product is 22.0 g/L C3434 (Citric Acid, trisodium salt, dihydrate); 7.3 g/L C0759 (Citric Acid, anhydrous); and 24.5 g/L G7528 (D-(+)-Glucose).

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Mingming Yang et al.
Experimental and therapeutic medicine, 20(2), 1253-1260 (2020-08-09)
The p53 gene is well known as a key tumor suppressor gene; it is vital for hematopoietic stem cell differentiation and growth. In the present study, the change of platelets (PLTs) in p53 knockout mice (p53-/- mice) was investigated. The
Interaction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo
Katz SG, et al.
Molecular and Cellular Biology, 22(9), 3121-3128 (2002)
Isolation, expansion and characterisation of mesenchymal stem cells from human bone marrow, adipose tissue, umbilical cord blood and matrix: a comparative study
Secunda R, et al.
Cytotechnology, 67(5), 793-807 (2015)
Comparison of equine platelet function and survival in whole blood collected in acid-citrate-dextrose solution or citrate-phosphate-dextrose-adenine solution
Bozorgmanesh R, et al.
Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology, 46(2), 262-268 (2017)
Zezhou Zhao et al.
FEBS open bio, 10(10), 2021-2039 (2020-10-06)
Cervicovaginal secretions, or their components collected, are referred to as cervicovaginal lavage (CVL). CVL constituents have utility as biomarkers and play protective roles in wound healing and against HIV-1 infection. However, several components of cervicovaginal fluids are less well understood

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