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Merck

L8662

L-Lysine monohydrochloride

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications

Sinónimos:

(S)-2,6-Diaminohexanoic acid monohydrochloride

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About This Item

Fórmula lineal:
H2N(CH2)4CH(NH2)CO2H·HCl
Número CAS:
Peso molecular:
182.65
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
211-519-9
MDL number:
Beilstein/REAXYS Number:
3563889

Nombre del producto

L-Lysine monohydrochloride, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

InChI key

BVHLGVCQOALMSV-JEDNCBNOSA-N

InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

SMILES string

OC([C@@H](N)CCCCN)=O.[H]Cl

biological source

non-animal source

agency

meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

assay

98.5-101.0%

form

powder

quality

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

263 °C (dec.) (lit.)

solubility

H2O: 100 mg/mL

application(s)

pharmaceutical (small molecule)

Quality Level

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Application


  • Scientific opinion on the presence of DNA in the feed additives consisting of concentrated liquid l-lysine, l-lysine monohydrochloride and concentrated liquid l-lysine monohydrochloride produced by Escherichia coliNITE BP-02917 for all animal species (METEX NOOVISTAGO).: This study explores the presence of DNA in l-lysine monohydrochloride and its variants used in animal feed, addressing safety concerns associated with genetic material in feed products (EFSA Panel et al., 2023).

  • Safety and efficacy of a feed additive consisting of concentrated liquid l-lysine, l-lysine monohydrochloride and concentrated liquid l-lysine monohydrochloride produced by Escherichia coliNITE BP-02917 for all animal species (Metex NoovistaGo).: Evaluates the safety and efficacy of l-lysine monohydrochloride in animal feed, contributing to a better understanding of its use and regulatory compliance (EFSA Panel et al., 2022).

  • Safety and efficacy of a feed additive consisting of l-lysine monohydrochloride and l-lysine sulfate produced by fermentation with Corynebacterium glutamicumCGMCC 17927 for all animal species (Barentz Animal Nutrition B.V.).: This publication assesses the safety and effectiveness of l-lysine monohydrochloride and l-lysine sulfate in various animal feeds, ensuring they meet health and nutritional standards (EFSA Panel et al., 2022).

  • Safety and efficacy of a feed additive consisting of l-lysine monohydrochloride and l-lysine sulfate produced by Corynebacterium glutamicum CGMCC 14498 for all animal species (Kempex Holland BV).: Investigates the implications of using l-lysine monohydrochloride and l-lysine sulfate in feed, focusing on their impact on animal health and growth (EFSA Panel et al., 2021).

  • Safety and efficacy of the feed additives concentrated liquid l-lysine (base) and l-lysine monohydrochloride produced by Corynebacterium glutamicum KCCM 80183 for all animal species (CJ Europe GmbH).: Analyzes the safety and benefits of concentrated liquid l-lysine and l-lysine monohydrochloride, detailing their advantages and regulatory approval for use in feed (EFSA Panel et al., 2021).


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Guntur Fibriansah et al.
Nature communications, 6, 6341-6341 (2015-02-24)
Dengue virus (DENV) infects ~400 million people annually. There is no licensed vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a naturally occurring dengue infection consists of highly neutralizing antibodies. Here we show that
Alexander Leitner et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), 9455-9460 (2014-06-19)
The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years. Thus far, such analyses have used almost exclusively homobifunctional, amine-reactive cross-linking reagents. Here
Lunzhi Dai et al.
Nature chemical biology, 10(5), 365-370 (2014-04-01)
We report the identification of a new type of histone mark, lysine 2-hydroxyisobutyrylation (Khib), and identify the mark at 63 human and mouse histone Khib sites, including 27 unique lysine sites that are not known to be modified by lysine
Przemyslaw Nogly et al.
IUCrJ, 2(Pt 2), 168-176 (2015-04-14)
Lipidic cubic phases (LCPs) have emerged as successful matrixes for the crystallization of membrane proteins. Moreover, the viscous LCP also provides a highly effective delivery medium for serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs). Here, the adaptation of
Bryan J Wilkins et al.
Science (New York, N.Y.), 343(6166), 77-80 (2014-01-05)
Metaphase chromosomes are visible hallmarks of mitosis, yet our understanding of their structure and of the forces shaping them is rudimentary. Phosphorylation of histone H3 serine 10 (H3 S10) by Aurora B kinase is a signature event of mitosis, but

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