USP

Melatonina

Name: Melatonina
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

N-Acetil-5-metoxitriptamina

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About This Item

Fórmula empírica (notación de Hill):

C₁₃H₁₆N₂O₂

Número CAS:

73-31-4

Peso molecular:

232.28

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329750346

MDL number:

MFCD00005655

Beilstein/REAXYS Number:

205542

Nombre del producto

Melatonina, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)

SMILES string

COc1ccc2[nH]cc(CCNC(C)=O)c2c1

InChI key

DRLFMBDRBRZALE-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

melatonin

manufacturer/tradename

USP

mp

116.5-118 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Categorías relacionadas

Analytical Reference Materials for Pharma QC

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Application

Melatonin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solutions for assay, performance tests, strength, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):

Melatonin Tablets
Melatonin

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Melatonin Tablets

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 37(6), 5144-5144 (2013)

Melatonin

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 37(4), 5143-5143 (2020)

Melatonin regulation as a possible mechanism for probiotic (VSL#3) in irritable bowel syndrome: a randomized double-blinded placebo study.

Reuben K Wong et al.

Digestive diseases and sciences, 60(1), 186-194 (2014-08-06)

Probiotics have treatment efficacy in irritable bowel syndrome (IBS), but the exact mechanism remains obscure. One hypothesis is the mediation of melatonin levels, leading to changes in IBS symptoms. The purpose of this study was to evaluate the effects of

Extrapineal melatonin: sources, regulation, and potential functions.

Darío Acuña-Castroviejo et al.

Cellular and molecular life sciences : CMLS, 71(16), 2997-3025 (2014-02-21)

Endogenous melatonin is synthesized from tryptophan via 5-hydroxytryptamine. It is considered an indoleamine from a biochemical point of view because the melatonin molecule contains a substituted indolic ring with an amino group. The circadian production of melatonin by the pineal

Melatonin reduces cardiac morbidity and markers of myocardial ischemia after elective abdominal aortic aneurism repair: a randomized, placebo-controlled, clinical trial.

Ismail Gögenur et al.

Journal of pineal research, 57(1), 10-15 (2014-04-09)

The aim was to examine the effect of perioperative melatonin treatment on clinical cardiac morbidity and markers of myocardial ischemia in patients undergoing elective surgery for abdominal aortic aneurism. Reperfusion injury results in increased cardiac morbidity in patients undergoing surgery

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