1.41544
Parteck® MXP (Polyvinyl alcohol 3-82)
EMPROVE® ESSENTIAL, Ph. Eur.
別名:
Parteck® Polyvinyl alcohol, PVA, Polyvinyl alcohol
ログインで組織・契約価格をご覧ください。
サイズを選択してください
表示を変更する
この商品について
agency
Ph. Eur.
Quality Segment
product line
EMPROVE® ESSENTIAL
form
powder
application(s)
pharmaceutical
solid formulation
solubility enhancement
storage temp.
15-25°C
InChI
1S/C2H4O/c1-2-3/h2-3H,1H2
InChI key
IMROMDMJAWUWLK-UHFFFAOYSA-N
General description
With a lower degree of hydrolysis along the PVA chain, Parteck® MXP 3-82 Polyvinyl alcohol is especially beneficial in forming strong interactions with hydrophobic drug molecules – in the solid state and in solution. Due to this, Parteck® MXP 3-82 excipient has very high capabilities as a precipitation inhibitor and can maintain high levels of supersaturation for physiologically relevant timescales. As a result, Parteck® MXP 3-82 Polyvinyl alcohol can provide solubility enhancement for even the most challenging molecules.
Application
Parteck® MXP 3-82 is a PVA-based excipient that is used in Hot Melt Extrusion for Solubility Enhancement in oral solid dosage forms.
Features and Benefits
- Superior supersaturation performance via precipitation inhibition
- High thermostability up to 250°C, extending the potential application range
- Stable high drug loads and suitability with a broad range of APIs
- Flexible release kinetics
- Compatible with several downstream processing capabilities, like direct compression, continuous manufacturing, thin film extrusion and 3D printing
- Optimized powder properties for excellent performance in the HME process
- Suitable polymer properties for HME, spray drying and 3D printing processes
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
No data available
flash_point_c
No data available
Emprove®プログラムを使用してGMPを遵守します。
Emprove® Dossiersで資格認定を加速し、コンプライアンスを維持し、時間を節約しましょう。
Dossiers をダウンロード
注意: EmproveSuite.comに移動します。ユーザー名とパスワードはSigmaAldrich.comとは別のもので、異なる場合があります。
無料会員登録すると、数分でEmprove® Dossiersにアクセスできます。 購読プランをアップグレードして、Emprove® Suiteの高度でカスタマイズされたコンテンツをアンロックしてください。
お探しのものが見つかりませんか？Emprove® プログラムのヘルプページをご覧ください。.