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Merck

48-691MAG

MILLIPLEX® Human Cell Health Panel

Human Cell Health 16-Plex Panel

Synonym(s):

CH multiplex kit, Human cell health multiplex kit, Luminex CH panel, Luminex human cell health immunoassay, MILLIPLEX® Human Cell Health Magnetic Bead Panel, Millipore cell health panel, cell health multiplex kit, cellular fingerprinting assay

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About This Item

UNSPSC Code:
41121800
NACRES:
NB.15

Key Documents

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Quality Level

200

species reactivity

human

assay range

intra-assay cv: ≤14%, inter-assay cv: ≤22%

technique(s)

multiplexing: suitable (: Suitable)

input

sample type cell lysate
cell lysate

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

General description

The analytes in this panel include key markers of apoptosis (e.g., Cleaved PARP, CHOP), autophagy (LC3B), DNA damage (Phospho-Histone H2A.x), cell proliferation (Ki67), and stress response (HSP70, GRP78), providing a comprehensive snapshot of cellular health. These biomarkers are critical for monitoring cellular responses to drug treatment, environmental stress, and disease progression, making the panel ideal for toxicology studies, cancer research, and pathway analysis. Their multiplexed detection enables efficient profiling of multiple pathways from limited sample volumes.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 16 analytes in cell lysate samples to support pathway analysis and enhance the reliability of comparative protein expression studies.

Analytes Included: CHOP, Cyclin B1, Complex IV, Ki67, LC3B, HIF-1α, Polyubiquitin (K48-linkage), HSP70, Cleaved PARP, GRP78, Phospho-eIF4B (Ser422), Phospho-NF-κB (Ser536), Phospho-Histone H2A.x (Ser139), Phospho-Histone H3 (Ser10), Phospho-p53 (Ser15), Phospho-RNA Pol II (Ser2)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).

Features and Benefits

  • Simultaneously measures 16 key markers of cell health in a single assay
  • Covers apoptosis, autophagy, DNA damage, proliferation, and stress response pathways
  • Ideal for studying cellular responses to drug treatment, disease, and environmental stress
  • High sensitivity and reproducibility using Luminex® xMAP® technology
  • Suitable for limited sample volumes and high-throughput analysis

Legal Information

Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

Storage Class

10 - Combustible liquids

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
48-691MAG04065272078665

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