8.51029
N-Biotinyl-NH-(PEG)2-COOH . DIPEA (20 atoms)
Novabiochem®
別名:
N-Biotinyl-NH-(PEG)₂-COOH . DIPEA (20 atoms), O-(N-Biotinyl-3-aminopropyl)-O′-(N-glutaryl-3-aminopropyl)-diethyleneglycol · DIPEA
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この商品について
実験式（ヒル表記法）:
C25H44N4O8S · xC8H19N
CAS番号:
分子量:
560.70
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.22
Quality Segment
product line
Novabiochem®
assay
≥95.0% (HPLC), ≥98% (TLC)
form
powder
reaction suitability
reaction type: Biotinylations
manufacturer/tradename
Novabiochem®
mp
131-136 °C
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
S1[C@H]([C@H]2NC(=O)N[C@H]2C1)CCCCC(=O)NCCOCCOCCOC(=O)O.N(C(C)C)(C(C)C)CC
InChI
1S/C17H29N3O7S.C8H19N/c21-14(18-5-6-25-7-8-26-9-10-27-17(23)24)4-2-1-3-13-15-12(11-28-13)19-16(22)20-15;1-6-9(7(2)3)8(4)5/h12-13,15H,1-11H2,(H,18,21)(H,23,24)(H2,19,20,22);7-8H,6H2,1-5H3/t12-,13-,15-;/m0./s1
InChI key
YOALVTBRBBZXGM-HZPCBCDKSA-N
General description
The use of this novel biotin derivative incorporates a hydrophilic 20 atom PEG spacer between the peptide and biotin. This not only greatly improves the solubility of the resultant peptide, but reduces steric hindrance between the peptide and biotin, leading to better avidin binding and higher biological activity. The biotin-PEG derivative can be easily incorporated using any standard coupling method as the final step in SPPS, immediately prior to cleavage of the peptide from the resin.
Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis
Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis
Analysis Note
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (50 mg in 1 ml NMP): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (50 mg in 1 ml NMP): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Replaces: 01-63-0133
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable