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Merck

PRCYTA-40K

MILLIPLEX® Non-Human Primate Cytokine/Chemokine/Growth Factor Panel A

Synonym(s):

monkey cytokine multiplex kit, non-human primate cytokine panel, primate immunology assay

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About This Item

NACRES:
NA.47
UNSPSC Code:
12352200

description

Configurable Non-Human Primate Cytokine/Chemokine/Growth Factor Panel A 48-Plex

species reactivity

nonhuman primates

manufacturer/tradename

Milliplex®

packaging

1 ea of

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)

assay range

inter-assay cv: <20%
intra-assay cv: <10%
inter-assay cv: <30%
(TFN-α)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 48 analytes in non-human primate serum, plasma, and cell culture supernatants.

Analytes included: BCA-1, sCD137, CD40L, Eotaxin, sFASL, FGF-2, Fractalkine, G-CSF, GM-CSF, Granzyme A, Granzyme B, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-15, IL-16, IL-17A, IL-17E, IL-18, IL-21, IL-22, IL-23, IL-28A, IL-31, IL-33, IP-10, I-TAC, MCP-1, MIG, MIP-1α, MIP-1β, MIP-3α, Perforin, RANTES, TGFα, TNFα, TNFβ, VEGF-A Note: RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Non-Human Primate Specific: Designed specifically for non-human primate samples, making it ideal for translational research.

Configurable Panel: Users can design their own multiplex kit by selecting from the available analytes.

Comprehensive Multiplexing: Simultaneous quantification of up to 48 analytes including cytokines, chemokines, and growth factors in a single assay.

Verified Dilution Guidelines: Includes specific instructions for analytes like RANTES and IL-8 to ensure optimal performance.

Trusted Technology: Utilizes Luminex® xMAP® technology, a gold standard in multiplex biomarker analysis.

Largest multiplex panel for non-human primates: This unmatched breadth empowers researchers to maximize data output from minimal sample volume, enabling comprehensive immune profiling in NHP models with unparalleled efficiency and sensitivity.

General description

Cytokines are small proteins secreted by immune cells that regulate immune responses, hematopoiesis, and lymphocyte development, including interleukins, interferons, and chemokines. Growth factors, which promote cell growth and proliferation, share structural and functional similarities with cytokines and act through specific receptors on target cells. Unlike hormones produced by specialized glands, both cytokines and growth factors can be secreted by various cell types, and their tightly regulated expression is crucial; dysregulation can lead to diseases such as infections, autoimmune disorders, and cancer. Research on these molecules is essential for understanding the immune system and developing therapeutic strategies, with non-human primates serving as important models due to their genetic similarity to humans.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
PRCYTA-40K-0204065266528909
PRCYTA-40K-2204065266529104
PRCYTA-40K-04C04065266529401
PRCYTA-40K-03C04065266529395
PRCYTA-40K-3204065266529203
PRCYTA-40K-14C04065266529500
PRCYTA-40K-21C04065266529579
PRCYTA-40K-0804065266528961
PRCYTA-40K-3404065266529227
PRCYTA-40K-4204065266529302
PRCYTA-40K-0904065266528978
PRCYTA-40K-2504065266529135
PRCYTA-40K-0704065266528954
PRCYTA-40K-1804065266529067
PRCYTA-40K-2004065266529081
PRCYTA-40K-25C04065266529616
PRCYTA-40K-10C04065266529463
PRCYTA-40K-34C04065266529708
PRCYTA-40K-19C04065266529555
PRCYTA-40K-1104065266528992
PRCYTA-40K-16C04065266529524
PRCYTA-40K-2804065266529166
PRCYTA-40K-1304065266529012
PRCYTA-40K-1604065266529043

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